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- Title
Inhibition of bacteria isolated from human specimens by selected marine-origin extracts.
- Authors
Ibrahim, Hassan A. H.; Shaaban, Mohamed T.; Hanafi, Amer A. M.; Abdelsalam, Khaled M.
- Abstract
The current study was suggested for treating bacteria previously isolated from human faeces and urine samples by the bioactive compounds extracted from marine origin. The three bacteria used in this study were fully identified as; Escherichia col i MK106369.1, Klebsiella pneumonia MK106370.1, and Staphylococcus aureus MK106371.1 in our previous work. The tested samples were sponge (Negombata magni fica, Siphonochalina siphonella, and Hyrtios erectus), soft coral (Sarcophyton glaucum and Xenia macrospiculata) and mangrove (Avicennia marina). On the other side, the highest activi ty of crude extracts inhibi ted identified bacteria was recorded by those of A. marina, while, the lowest activity of crude extracts which inhibited them was recorded by S. glaucum. The minimal inhibi tor concentration (MIC) values for di fferent crude extracts ranged between 25 and 75 mgml -1. The major consti tuents of the potent extracts were determined by the GC-MS and they were; fatty acids (tridecanoic acid, hexadecanoic acid, pentadecanoic acid, oleanoic acid, etc.) and their esters, terpenoids, carotenoids, other compounds such as Betul in, Cryptoflavin, Zeaxanthin, Reserpine, and Amiodarone. These findings confirm that marine origin extracts, especially from mangrove leaves, may be considered as a promising source for treating bacterial resistance to antibiotics.
- Subjects
MARINE bacteria; DRUG resistance in bacteria; STAPHYLOCOCCUS aureus; PALMITIC acid; ALCYONACEA; KLEBSIELLA pneumoniae; EXTRACTS
- Publication
Egyptian Journal of Experimental Biology (Botany), 2020, Vol 16, Issue 1, p91
- ISSN
1687-7497
- Publication type
Article
- DOI
10.5455/egyjebb.20200509032540