We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Relationship between serum vitamin level and diabetes and diabetic foot.
- Authors
Ren-Yan Huang; Ling Wang; Yin-Feng Zhang; Feng Xu; Guo-Bing Liu
- Abstract
Objective: To explore the relationship between the changes of serum vitamin level in patients with type 2 diabetes mellitus and diabetic foot. Method Totally 68 patients with type 2 diabetes admitted to our hospital from September 2018 to March 2019 were selected as observation group (DM group: Totally 32 patients without diabetic foot group, DM+DF group of 34 patients) and 68 patients with physical examination in our hospital (healthy control group) at the same time, and the serum vitamin levels of the two groups of patients were compared.On this basis, the relationship between serum vitamin level and diabetic foot was further explored. Results There were differences between the observation group and the healthy control group in the history of hypertension, 2h postprandial blood glucose and glycosylated hemoglobin between the two groups (all P < 0.001).Compared with the vitamin levels of the observation group and the healthy control group, there were statistical differences in vitamin B6 and vitamin B1 and vitamin B9 and Vitamin C and vitamin D (P < 0.001), but there were no differences in vitamin A, vitamin B2 and vitamin E (P > 0.05). Compared with the vitamin levels in the two subgroups of the observation group,there were statistical differences in vitamin B6 and vitamin B1 and vitamin B9 and Vitamin C (P < 0.001). Logistic regression analysis showed that vitamin B6[OR95% CI 0.633(0.434,0.924)], vitamin B1[OR95% CI 0.705(0.524,0.949), vitamin B9[OR95% CI 0.248(0.063,0.978), and Vitamin C[OR95% CI 0.584(0.409,0.835) were risk factors for diabetic foot. Conclusion Vitamin B6, vitamin B1, vitamin B9 and Vitamin C can be used as indicators to predict the risk of DF in T2DM patients.
- Subjects
BLOOD serum analysis; DIABETIC foot; TYPE 2 diabetes; HYPERTENSION; LOGISTIC regression analysis
- Publication
Journal of Hainan Medical University, 2019, Vol 25, Issue 16, p26
- ISSN
1007-1237
- Publication type
Article