We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Reversible Redox Activity by Ion-pH Dually Modulated Duplex Formation of i-Motif DNA with Complementary G-DNA.
- Authors
Chang, Soyoung; Kim, Seon Jeong; Shin, Su Ryon; Oskui, Shirin Mesbah; Kilic, Tugba; Avci, Huseyin; Lee, Chang Kee; Bae, Hojae; Jung, Sung Mi
- Abstract
The unique biological features of supramolecular DNA have led to an increasing interest in biomedical applications such as biosensors. We have developed an i-motif and G-rich DNA conjugated single-walled carbon nanotube hybrid materials, which shows reversible conformational switching upon external stimuli such as pH (5 and 8) and presence of ions (Li+ and K+). We observed reversible electrochemical redox activity upon external stimuli in a quick and robust manner. Given the ease and the robustness of this method, we believe that pH- and ion-driven reversible DNA structure transformations will be utilized for future applications for developing novel biosensors.
- Subjects
CARBON nanotubes; DNA; BIOSENSORS
- Publication
Nanomaterials (2079-4991), 2018, Vol 8, Issue 4, p226
- ISSN
2079-4991
- Publication type
Article
- DOI
10.3390/nano8040226