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- Title
术前磁共振特征与成人胶质母细胞瘤患者生存期的相关性分析.
- Authors
王龙; 李学刚; 张超; 李雨泓; 陈图南; 冯华; 李飞
- Abstract
Objective To investigate the correlation between preoperative MRI features and survival time of adult glioblastoma patients. Methods The clinical data of 123 IDH wild type GBM patients admitted to the Department of Neurosurgery, the First Affiliated Hospital of the Army Military Medical University from January 2016 to January 2020 were analyzed retrospectively. Kaplan Meier method was used to evaluate the survival time, and log rank was used to analyze the influence of tumor MRI characteristics, location, size, edema, KPS score, and extent of surgical resection degree on the survival time. Cox regression was used to analyze the risk factors related to the survival of GBM patients. Results Univariate analysis showed that preoperative MRI features (P=0.000), tumor location (P=0.046), and surgical resection degree (P=0.000) were significantly related to survival time. Cox regression analysis showed that MRI showed that central necrosis (HR=2.157, 95% CI=1.214-3.831, P=0.009) and multiple necrosis (HR=6.185, 95% CI=3.061-12.497, P=0.000) were risk factors affecting the survival of GBM patients. Conclusion MRI shows central necrosis and multiple tumors, which are the hallmarks of poor prognosis of GBM.
- Publication
Journal of Clinical Neurosurgery / Linchuang Shenjingwaike Zazhi, 2022, Vol 19, Issue 6, p614
- ISSN
1672-7770
- Publication type
Article
- DOI
10.3969/j.issn.1672-7770.2022.06.003