We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
A Serious Complication of Selected Internal Radiation Therapy: Case Report and Literature Review.
- Authors
SJOQUIST, KATRIN M.; GOLDSTEIN, DAVID; BESTER, LOURENS
- Abstract
The use of selective internal radiation therapy (SIRT) with SIR-Spheres® (Sirtex, Sydney, Australia) is increasingly recognized as a potential therapeutic modality of primary and secondary malignant liver tumors. A number of treatment- related complications have been described despite technical expertise and detailed pretreatment investigations to assess suitability. We describe a case of gastric ulceration from nontargeted deposition of SIR-spheres® in the gastric mucosa with life-threatening consequences. This case highlights the need for careful screening and appropriate patient selection, and the need to recognize ulceration from SIRT as a potential complication of treatment. The characteristic endoscopic, radiologic, and histopathologic findings are illustrated and recommendations are reviewed with regard to the current literature.
- Subjects
RADIOISOTOPE therapy; COLON tumors; DRUG delivery systems; DRUG administration; METASTASIS; PEPTIC ulcer; RADIOPHARMACEUTICALS; RADIOTHERAPY; RECTUM tumors
- Publication
Oncologist, 2010, Vol 15, Issue 8, p830
- ISSN
1083-7159
- Publication type
Case Study
- DOI
10.1634/theoncologist.2010-0074