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- Title
Impact of Nutritional Status, Loss of Weight or Appetite, Dysphagia, and Micronutrient Deficiencies on All-Cause Mortality in Older Patients.
- Authors
AYDIN, Elifnur; SOYSAL, Pınar; PASİN, Özge
- Abstract
Introduction: This study aimed to evaluate the effect of different indicators of nutritional status, including undernutrition, risk of malnutrition, malnutrition, weight loss or loss of appetite, dysphagia, and deficiencies of vitamin B12, folate, and vitamin D, on mortality in older patients. Method: This retrospective cohort study enrolled 1911 older outpatients (81.0±13.0, 70.8% female). Mini Nutritional Assessment, Eating Assessment Tool-10, and the Council on Nutrition Appetite Questionnaire were used to determine nutritional status, dysphagia, and loss of appetite, respectively. The patient or the caregiver was asked whether the patient had lost weight in the last 3 months. Vitamin B12 and folate deficiencies were defined as <200 pg/mL and <3 ng/mL, respectively. Results: In terms of survival analyses, the results obtained from Cox regression analysis showed that the effects of folate and B12 vitamin deficiencies on the hazard ratio (HR) were not significant (p<0.05), but vitamin D deficiency was related to 1.57 times higher mortality (p<0.001). The HR value for individuals with undernutrition, risk of malnutrition, and malnutrition were 2.94, 2.19, and 4.46 times higher, respectively (p<0.001). Individuals with dysphagia have a 1.83-fold higher HR (p<0.001). Reduced appetite leads to a 1.63 times higher HR (p<0.001). For individuals with a weight loss of 3 or more, the hazard risk is 2.42 times higher (p<0.001). Conclusion: The results of this study show that nutritional status, loss of weight or appetite, dysphagia, and micronutrient deficiencies are associated with all-cause mortality.
- Subjects
WEIGHT loss; APPETITE loss; DEFICIENCY diseases; NUTRITIONAL status; OLDER patients
- Publication
Bezmialem Science, 2024, Vol 13, pS11
- ISSN
2148-2373
- Publication type
Abstract