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- Title
Effect of Narrow Band UVB on normal flora of lesional and normal skin in psoriatic patients.
- Authors
Mahmood Farshchian; Elaheh Soltanie; Leila Moosavee; Hossein Mahjoob; Abbas Zamanian; Haleh Nazerian
- Abstract
Background and Aim: Psoriasis is a chronic inflammatory dermatosis that affects 0.6% to 4.8% of the general population. Our aim was to compare the effect of narrow band UVB (NBUVB) on normal flora of cutaneous plaques and normal skin in psoriatic patients. Methods: Twenty psoriatic patients without any contraindication of phototherapy were enrolled in this study. Samples from psoriatic lesions and adjacent normal skin, before and after phototherapy with NB-UVB were taken. Patients were treated with NB-UVB three times weekly until complete remission. Finally, quantity of normal cutaneous flora on normal and involved skin, before and after treatment was compared. Results: The mean±SD of the NB-UVB sessions and the mean cumulative dose were 26.35±4.95 and 2.05±0.57 J/cm2, respectively. The number of Staphylococcus epidermidis, S. aureus and diphtheroids on psoriatic plaques reduced after phototherapy. Conclusuion: The quantity of normal cutaneous flora on normal skin is less than psoriatic plaques, and it reduced on normal and involved skin after phototherapy.
- Subjects
PSORIASIS treatment; PHOTOTHERAPY; STAPHYLOCOCCUS epidermidis; STAPHYLOCOCCUS aureus; SKIN physiology; HEALTH outcome assessment
- Publication
Dermatology & Cosmetic, 2012, Vol 3, Issue 2, p83
- ISSN
2008-7470
- Publication type
Article