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- Title
Vitamin A Metabolism and Adipose Tissue Biology.
- Authors
Frey, Simone K.; Vogel, Silke
- Abstract
In recent years, the importance of vitamin A in adipose tissue biology, obesity and type II diabetes has become apparent. This review focuses on recent developments within the area of vitamin A and adipose tissue biology. Adipose tissue has an active vitamin A metabolism as it not only stores vitamin A but retinol is also converted to its active metabolite retinoic acid. Several mouse models point to a relationship between vitamin A metabolism and the development of adiposity. Similarly, in vitro studies provide new molecular mechanisms for the function of different forms of vitamin A and retinol- or retinoic acid-binding proteins in adipose tissue.
- Subjects
VITAMIN A; NUTRIENT interactions; ADIPOSE tissues; OBESITY; TYPE 2 diabetes; TRETINOIN
- Publication
Nutrients, 2011, Vol 3, Issue 1, p27
- ISSN
2072-6643
- Publication type
Article
- DOI
10.3390/nu3010027