Back to matchesWe found a matchYour institution may have access to this item. Find your institution then sign in to continue.TitleHolford NHG and Sheiner LB 'Understanding the Dose-Effect Relationship-Clinical Application of Pharmacokinetic-Pharmacodynamic Models', Clin Pharmacokin 6:429-453 (1981)-The Backstory.AuthorsHolford, NickPublicationAAPS Journal, 2011, Vol 13, Issue 4, p662ISSN1550-7416Publication typeArticleDOI10.1208/s12248-011-9306-5