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- Title
Sesquiterpenoids From the Leaves of Datura metel L.
- Authors
Liu, Yan; Zhuang, Leixin; Tan, Jinyan; Zhou, Yuanyuan; Jiang, Peng; Fan, Ruifeng; Kuang, Haixue; Yang, Bingyou
- Abstract
In the course of chemical investigations of Datura metel L., a new sesquiterpenoid, dmetelin J (1) was isolated from the leaves, along with the 4 known compounds apocynol A (2), blumenol B (3), megastigmane (4), and (+)-dehydrovomifoliol (5). Structure elucidation was performed by spectroscopic techniques, including 1- and 2-dimensional NMR spectroscopy and HRESIMS. Compounds 2, 3, and 5 were isolated from the Solanaceae for the first time. All isolated compounds were subjected to anti-inflammatory activity evaluation.
- Subjects
SESQUITERPENES; ANTI-inflammatory agents; NUCLEAR magnetic resonance spectroscopy; CHEMILUMINESCENCE assay
- Publication
Natural Product Communications, 2023, Vol 18, Issue 7, p1
- ISSN
1934-578X
- Publication type
Article
- DOI
10.1177/1934578X221128097