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- Title
Can reactive donor screening results be presumed false positive following unstandardized testing procedures?
- Authors
Sepetiene, Ramune; Galli, Claudio; Bhatnagar, Sonu; Ali, Mohamed; Orjuela, Guillermo; Olson, Ellen; Robbins, Ninette; Kang, Jason
- Abstract
Combining these results with those of a rapid, qualitative HCV Ab assay and quantitative HCV cAg test, they report acute hepatitis C case positivity of 8.1%. In their original article recently published in I Vox Sanguinis i , Lucey et al. [[1]] presented an evaluation of signal-to-cut-off ratios (S/CO) of an approved antibodies against hepatitis C virus (anti-HCV) screening assay (Architect Anti-HCV antibody assay; Abbott GmbH, Germany), along with an alternative antibody test (Standard Q HCV Ab test; SD Biosensor, Korea) and an HCV core antigen (HCV cAg) test (Architect HCV Ag; Abbott GmbH, Germany) in order to propose a blood donor screening algorithm containing supplemental testing using screened reactive HCV samples ( I n i = 470).
- Subjects
MEDICAL screening; RAPID diagnostic tests; CENTRIFUGATION; AIDS serodiagnosis
- Publication
Vox Sanguinis, 2023, Vol 118, Issue 9, p807
- ISSN
0042-9007
- Publication type
Article
- DOI
10.1111/vox.13490