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- Title
Dental caries in HIV‐infected children and adolescents: A systematic review with meta‐analysis.
- Authors
Faé, Daniele Sorgatto; de Aquino, Sibele Nascimento; Verner, Francielle Silvestre; Lemos, Cleidiel Aparecido Araujo
- Abstract
This study aimed to evaluate and compare the risk of dental caries in between human immunodeficiency virus (HIV)‐infected and uninfected children and adolescents. An electronic search was performed on PubMed/MEDLINE, Web‐of‐Science, Scopus, LILACS, ProQuest, and ClinicalTrials.gov up to May 2022. The critical appraisal checklist developed by the Joanna Briggs Institute was used to evaluate the quality of the included studies. Meta‐analysis was performed using the RevMan 5.4. Sixteen studies were included. A total of 3231 participants were evaluated, including 1701 and 1530 HIV‐infected and uninfected children and adolescents, respectively. The meta‐analysis revealed a higher risk of dental caries for primary dentitions in HIV‐infected children and adolescents by decayed, missing, filled tooth (dmft) (SMD:0.34; p = 0.006) and decayed, missing, filled surface (dmfs) scores (SMD:0.37; p = 0.001). Similar results were observed for permanent dentition, with increased dental caries in HIV‐infected children and adolescents with DMFT (SMD:0.32; p = 0.003) and DMFS (SMD:1.78; p < 0.0001) scores. Regarding the quality assessment, most of the included studies were moderate or good quality. However, the certainty of the evidence of the outcomes was very low. This systematic review and meta‐analysis showed higher caries severity in permanent and deciduous teeth among HIV‐infected children and adolescents.
- Subjects
RISK assessment; RESEARCH funding; HIV-positive persons; PERMANENT dentition; SEVERITY of illness index; META-analysis; DESCRIPTIVE statistics; SYSTEMATIC reviews; MEDLINE; DECIDUOUS dentition (Tooth development); DENTAL caries; ONLINE information services; DATA analysis software; QUALITY assurance; EVALUATION; DISEASE risk factors; ADOLESCENCE; CHILDREN
- Publication
Oral Diseases, 2024, Vol 30, Issue 4, p1756
- ISSN
1354-523X
- Publication type
Article
- DOI
10.1111/odi.14637