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- Title
Development of a Guinea Pig Model of Chronic Asthma with Markedly Thickened Airway Walls: Two Studies Using This Animal Model.
- Authors
Yoshida, Minoru; Toda, Masao; Sagara, Hironori; Nakano, Yasuhiro; Hiyama, Takako; Fukuda, Takeshi
- Abstract
Provides information on a study which developed a guinea pig model of chronic asthma with markedly thickened airway walls by repeated antigen challenge in sensitized animals, to assess questions in regard to airway remodeling. Element which is thought to correspond to bronchial biopsy sites in humans; Overview of the model; Measurement of airway hyper-responsiveness.
- Subjects
GUINEA pigs as laboratory animals; ASTHMA; AIRWAY (Anatomy); RESPIRATION; ANTIGENS; BIOPSY
- Publication
International Archives of Allergy & Immunology, 2001, Vol 124, Issue 1-3, p276
- ISSN
1018-2438
- Publication type
Article
- DOI
10.1159/000053731