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- Title
Deciphering laminar-specific neural inputs with line-scanning fMRI.
- Authors
Yu, Xin; Qian, Chunqi; Chen, Der-yow; Dodd, Stephen J; Koretsky, Alan P
- Abstract
Using a line-scanning method during functional magnetic resonance imaging (fMRI), we obtained high temporal (50-ms) and spatial (50-μm) resolution information along the cortical thickness and showed that the laminar position of fMRI onset coincides with distinct neural inputs in rat somatosensory and motor cortices. This laminar-specific fMRI onset allowed us to identify the neural inputs underlying ipsilateral fMRI activation in the barrel cortex due to peripheral denervation-induced plasticity.
- Subjects
FUNCTIONAL magnetic resonance imaging; SOMATOSENSORY cortex; MOTOR cortex; PHENOTYPIC plasticity; NEURAL physiology; LABORATORY rats
- Publication
Nature Methods, 2014, Vol 11, Issue 1, p55
- ISSN
1548-7091
- Publication type
Article
- DOI
10.1038/nmeth.2730