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- Title
Briarenolides F and G, New Briarane Diterpenoids from a Briareum sp. Octocoral.
- Authors
Pei-Han Hong; Yin-Di Su; Jui-Hsin Su; Yung-Husan Chen; Tsong-Long Hwang; Ching-Feng Weng; Chia-Hung Lee; Zhi-Hong Wen; Jyh-Horng Sheu; Nai-Cheng Lin; Yueh-Hsiung Kuo; Ping-Jyun Sung
- Abstract
Two new briarane diterpenoids, briarenolides, F (1) and G (2), were isolated from an octocoral identified as Briareum sp. The structures of briaranes 1 and 2 were established by spectroscopic methods and by comparison of the spectroscopic data with those of known briarane analogues. Briarenolide F was proven to be the first 6-hydroperoxybriarane derivative and this compound displayed a significant inhibitory effect on the generation of superoxide anion by human neutrophils.
- Subjects
DITERPENES; ENZYME inhibitors; SUPEROXIDES; SPECTRUM analysis; CHEMICAL derivatives; CHEMICAL inhibitors
- Publication
Marine Drugs, 2012, Vol 10, Issue 5, p1156
- ISSN
1660-3397
- Publication type
Article
- DOI
10.3390/md10051156