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- Title
ICOS-ligand expression on plasmacytoid dendritic cells supports breast cancer progression by promoting the accumulation of immunosuppressive CD4<sup>+</sup> T cells.
- Authors
Burchell, Joy
- Abstract
This article discusses a study on the role of inducible costimulatory (ICOS)-ligand expression on plasmacytoid dendritic cell in the progression of breast cancer. It references a study by J. Faget et al. published in a 2012 issue of "Cancer Research". The study concludes that ICOS/ICOS-ligand interaction may increase antitumor immunity and may play a significant role in immunotherapy.
- Subjects
LIGANDS (Biochemistry); DENDRITIC cells; BREAST cancer research; IMMUNITY; IMMUNOTHERAPY
- Publication
Current Medical Literature: Breast Cancer, 2012, Vol 24, Issue 4, p148
- ISSN
0956-6511
- Publication type
Article