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- Title
Type of anti-thrombotic therapy for venous stenting in patients with non-thrombotic iliac vein lesions does not influence the development of in-stent restenosis.
- Authors
Tran, Maxwell A; Lakhanpal, Priya; Lakhanpal, Sanjiv; Satwah, Vinay K; Lakhanpal, Gaurav; Pappas, Peter J
- Abstract
Background: In patients receiving stents for symptomatic non-thrombotic iliac vein lesions, many clinicians prescribe anti-thrombotic medications. Whether or not anti-coagulation post-venous stenting improves stent patency is unknown. The aim of this investigation is to determine whether prophylactic post-operative anti-thrombotic therapy improves stent patency and/or prevents in-stent restenosis. Methods: The medical records and venous ultrasounds for 389 patients stented for non-thrombotic iliac vein lesions were retrospectively reviewed. Patients were categorized into three anti-thrombotic regimens: Clopidogrel, Aspirin and Clopidogrel, and Apixaban or Rivaroxaban. Patients were routinely assessed for restenosis and stent patency at 6, 26, and 52 weeks and treated with anti-thrombotics for 90 days. Results: Freedom from in-stent restenosis at 6, 26, and 52 weeks were Clopidogrel (91.50, 82.91, 80.95%), Aspirin and Clopidogrel (88.68, 80.03, 80.03%), and Apixaban or Rivaroxaban (91.03, 85.11, 83.18%). Primary patencies were Clopidogrel (98.77, 98.77, 98.10%), Aspirin and Clopidogrel (100, 95.74, 95.74%), and Apixaban or Rivaroxaban (98.70, 98.70, 96.71%). There were no statistically significant differences. Conclusions: The type of post-operative anti-thrombotic therapy for non-thrombotic iliac vein lesions does not appear to improve stent patency or prevent the development of in-stent restenosis.
- Subjects
CORONARY restenosis prevention; FIBRINOLYTIC agents; ANTICOAGULANTS; ASPIRIN; ILIAC vein; VASCULAR resistance; POSTOPERATIVE period; SURGICAL stents; TREATMENT effectiveness; RETROSPECTIVE studies; CLOPIDOGREL; RIVAROXABAN
- Publication
Phlebology, 2020, Vol 35, Issue 10, p805
- ISSN
0268-3555
- Publication type
Article
- DOI
10.1177/0268355520941385