We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Evaluation of carotid intima-media thickness, a marker of subclinical atherosclerosis, in children with cerebral palsy.
- Authors
Cece, Hasan; Yetisgin, Abdulkadir; Abuhandan, Mahmut; Yildiz, Sema; Calik, Mustafa; Karakas, Omer; Karakas, Ekrem; Iscan, Akin
- Abstract
Background: Respiratory and cardiovascular diseases are the most common causes of death in children with cerebral palsy. Objective: To evaluate sonographic carotid intima-media thickness, an early marker of atherosclerosis, in children with cerebral palsy and in healthy controls. Materials and methods: One hundred children with cerebral palsy (65 boys), mean age 6.2 (SD, 2.1) years, and 35 age-matched and sex-matched healthy controls were included. Common carotid artery intima-media thickness was measured sonographically. Differences between patients and controls were evaluated with an independent samples t-test. Results: Age, sex distribution and levels of serum lipids were comparable between patients and controls. Average, right and left carotid artery intima-media were thicker in patients compared with controls (mean ± SD, 0.61 ± 0.13 mm vs 0.40 ± 0.03 mm; 0.61 ± 0.14 mm vs 0.40 ± 0.03 mm; 0.61 ± 0.13 mm vs 0.40 ± 0.03 mm, respectively; all P < 0.001). Conclusion: Carotid intima-media is sonographically thicker in children with cerebral palsy compared with healthy controls, which may express an increased risk of atherosclerotic diseases.
- Subjects
ATHEROSCLEROSIS in children; CEREBRAL palsy; CARDIOVASCULAR diseases; CHILD death; ULTRASONIC imaging; SEX distribution; CAROTID artery; ATHEROSCLEROSIS
- Publication
Pediatric Radiology, 2012, Vol 42, Issue 6, p679
- ISSN
0301-0449
- Publication type
Article
- DOI
10.1007/s00247-012-2361-y