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- Title
T-Cell Acute Lymphoblastic Leukemia: A Report of 60 Patients from India.
- Authors
Advani, S.H.; Kamat, D.M.; Rao, D.N.; Gopal, R.; Nair, C.N.; Saikia, T.
- Abstract
60 patients studied at the Tata Memorial Hospital from January 1976 to December 1982 were diagnosed as having T-cell acute lymphoblastic leukemia (ALL) by nonimmune rosette formation with sheep red blood cells. The analysis revealed a high incidence of mediastinal mass (50%) and extramedullar infiltration at presentation. The majority of patients (62%) presented with a high WBC count (>50,000/mm3). Unipolar acid phosphatase activity was observed in 90% of patients. The remission rate with a combination treatment of adriamycin, vincristine and prednisolone was found to be 95%. Long-term survival was around 30%. More aggressive or innovative treatments will be needed to improve the results in T-cell ALL. Copyright © 1985 S. Karger AG, Basel
- Publication
Oncology, 1985, Vol 42, Issue 5, p282
- ISSN
0030-2414
- Publication type
Article
- DOI
10.1159/000226047