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- Title
Novel nucleophilic rearrangement of 1-substituted isoquinolines using an alcoholic sodium hydroxide solution.
- Authors
Terenin, V. I.; Volkov, A. A.; Ivanov, A. S.; Kabanova, E. V.
- Abstract
The reactions of 1-substituted isoquinolinium salts have been studied in the cases of the 1-isopropyl-2-methyl- and 2-methyl-1-cyclohexylisoquinolinium iodides using an alcoholic solution of sodium hydroxide. The possibility of preparing a wide range of spirocyclic ketones, alcohols, amino alcohols, and isochroman-3-ones has been demonstrated.
- Subjects
ISOQUINOLINE; NUCLEOPHILIC reactions; ALCOHOLS (Chemical class); SODIUM hydroxide; ORGANIC compounds
- Publication
Chemistry of Heterocyclic Compounds, 2011, Vol 47, Issue 1, p74
- ISSN
0009-3122
- Publication type
Article
- DOI
10.1007/s10593-011-0722-3