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- Title
Enterovirus D : A Small but Versatile Species.
- Authors
Filipe, Ines Cordeiro; Guedes, Mariana Soares; Zdobnov, Evgeny M.; Tapparel, Caroline
- Abstract
Enteroviruses (EVs) from the D species are the causative agents of a diverse range of infectious diseases in spite of comprising only five known members. This small clade has a diverse host range and tissue tropism. It contains types infecting non-human primates and/or humans, and for the latter, they preferentially infect the eye, respiratory tract, gastrointestinal tract, and nervous system. Although several Enterovirus D members, in particular EV-D68, have been associated with neurological complications, including acute myelitis, there is currently no effective treatment or vaccine against any of them. This review highlights the peculiarities of this viral species, focusing on genome organization, functional elements, receptor usage, and pathogenesis.
- Subjects
VACCINE effectiveness; NERVOUS system; SPECIES; GASTROINTESTINAL system; COMMUNICABLE diseases
- Publication
Microorganisms, 2021, Vol 9, Issue 8, p1758
- ISSN
2076-2607
- Publication type
Article
- DOI
10.3390/microorganisms9081758