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- Title
Hipoksik İskemik Ensefalopati Tanılı Bebeklerde Hipotermi Tedavisinin Sağ Ventrikül Sistolik Basıncı ve Pulmoner Tansiyon Üzerine Etkisi.
- Authors
BÜYÜKEREN, Melek; ÇELİK, Hasan Tolga; AYKAN, Hayrettin Hakan; CEBECİ, Kübra; KARAGÖZ, Tevfik; YİĞİT, Şule; YURDAKÖKa, Murat
- Abstract
Objective: Hypoxic ischemic encephalopathy (HİE) is a serious cause of central nervous system damage. To investigate the effect of hypothermia treatment on pulmonary arterial pressure and to compare the right ventricular systolic pressures before and after the hypothermia treatment in newborns with HİE who were treated with hypothermia. Material and Methods: The patients who were diagnosed as hypoxic-ischemic encephalopathy in Hacettepe University Faculty of Medicine Neonatal Intensive Care Unit between 2010-2016 were retrospectively reviewed. A total of 43 patients were included in the study. Echocardiography evaluation was carried out before and after the hypothermia treatment. Measurements of right ventricular systolic pressure (RVSP) and peak tricuspid regurgitation jet velocity were recorded. Results: RVSP values [median (25-75p) of 18 patients with pulmonary hypertension before and after the hypothermia treatment were 60 (57-81) and 25 (14-38) mmHg, respectively (p<0.05). Pulmonary hypertension improved after hypothermia in all patients who had pulmonary hypertension before hypothermia treatment. There was no increase in pulmonary artery pressures after hypothermia treatment in infants with HİE who were prescribed medication for pulmonary hypertension prior to hypothermia treatment. Conclusion: Hypothermia treatment in newborns with HİE did not increase in pulmonary arterial pressure.
- Subjects
SYSTOLIC blood pressure; CRITICAL care medicine; INTENSIVE care units; NEONATAL intensive care; PULMONARY hypertension; CEREBRAL anoxia-ischemia
- Publication
Turkiye Klinikleri Journal of Pediatrics / Türkiye Klinikleri Pediatri Dergisi, 2019, Vol 28, Issue 3, p103
- ISSN
1300-0381
- Publication type
Article
- DOI
10.5336/pediatr.2019-66143