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- Title
Translationally controlled tumour protein: A protein necessary for potyvirus intracellular multiplication that supports plant infection by unrelated viruses.
- Authors
Bruckner, Fernanda Prieto; Andrade, Patrícia Oliveira; de Souza Cascardo, Renan; Laliberté, Jean‐François; Alfenas‐Zerbini, Poliane
- Abstract
The multifunctional protein translationally controlled tumour protein (TCTP) was previously identified as necessary for infection by the potyvirus pepper yellow mosaic virus. Using turnip mosaic virus (TuMV) as a model to study potyvirus biology, we confirmed that TCTP has a positive effect on virus infection. Living cell confocal microscopy demonstrated that TCTP colocalises with 6K2‐tagged replication vesicles and with a perinuclear globular structure typically observed during potyvirus infection. Also, TCTP silenced protoplasts showed reduced virus accumulation, quantified by qRT‐PCR, which suggests an effect on virus replication, translation or other intracellular process. Finally, TCTP silencing in plants reduced the accumulation of two species belonging to Orthotospovirus and a Begomovirus genus, which are not closely related to potyviruses. The results suggest that TCTP is a general susceptibility factor to several unrelated viruses.
- Subjects
TOBACCO mosaic virus; TURNIP mosaic virus; VIRUS diseases; VIRAL replication; MULTIPLICATION; HOSPITAL central service departments
- Publication
Annals of Applied Biology, 2022, Vol 180, Issue 1, p90
- ISSN
0003-4746
- Publication type
Article
- DOI
10.1111/aab.12708