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- Title
Mycobacterium avium-intracellulare-associated acute interstitial nephritis: a rare cause of renal allograft dysfunction.
- Authors
Rawla, M. S.; Kozak, A.; Hadley, S.; LeCates, W. W.
- Abstract
Nontuberculous mycobacterium (NTM) infections are unusual in the renal transplant population. We present a case of disseminated Mycobacterium avium- intracellulare in a renal transplant recipient who was negative for human immunodeficiency virus infection. Our patient developed renal allograft dysfunction in the setting of disseminated disease and reduced immunosuppression. Transplant biopsy showed acute interstitial nephritis with granulomas and acid-fast bacilli. Acute renal failure resolved completely with further reductions in immunosuppression and anti-mycobacterial therapy. Our patient demonstrates the challenges in diagnosis and treatment of this rare infectious complication.
- Subjects
MYCOBACTERIUM; MYCOBACTERIA; MYCOBACTERIUM avium; INTERSTITIAL nephritis; KIDNEY diseases
- Publication
Transplant Infectious Disease, 2009, Vol 11, Issue 6, p529
- ISSN
1398-2273
- Publication type
Article
- DOI
10.1111/j.1399-3062.2009.00432.x