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- Title
Efficient generation of human natural killer cell lines by viral transformation.
- Authors
Vogel, B; Tennert, K; Full, F; Ensser, A
- Abstract
The article presents a study which describes the in vitro growth transformation of functional human natural killer (NK) cells by Herpesvirus saimiri (HVS), a primate rhadinovirus. It mentions that HVS transformation can be used to establish autologous or heterologous patient-specific NK cell lines. The use of patient-specific NK cell lines in studying functional defects in NK cell deficiencies is also tackled.
- Subjects
KILLER cells; HERPESVIRUS saimiri; CELL lines; IN vitro studies; CELL culture
- Publication
Leukemia (08876924), 2014, Vol 28, Issue 1, p192
- ISSN
0887-6924
- Publication type
Article
- DOI
10.1038/leu.2013.188