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- Title
ORALLY DISINTEGRATING TABLETS: RECENT ADVANCEMENT IN FORMULATION & NEW MARKET OPPORTUNITIES.
- Authors
Patil, A. M.; Patil, J. K.; Pawar, S. P.
- Abstract
Oral route is the most convenient route for drug administration due to the highest component of compliance mainly the pediatrics and geriatrics. Oral disintegrating tablets are those solid dosage forms when put on tongue, disintegrate or dissolve instantaneously, releasing the drug, within a few seconds without the need of water. Methods to improve patient's compliance have always attracted scientists towards the development of oral drug delivery systems such formulations provide an opportunity for product life extension in the many elderly persons which have difficulty in taking conventional oral dosage form (viz., solutions, suspensions, tablets, and capsules) because of hand tremors and dysphagia. Oral disintegrating tablets aim for designing dosage forms, convenient to be manufactured and administered, free of side effects, offering immediate release and enhanced bioavailability, to achieve better patient compliance. Fast disintegrating tablets have received ever-increasing demand during the last decade, and the field has become a rapidly growing area in the pharmaceutical industry. This article includes requirement for orally disintegrating tablets, orally disintegrating films, chewing gums, oral wafers and buccal patches, various technologies developed for formulated orally disintegrating dosage form, super disintegrating agents in the formulation, evaluation method.
- Subjects
DRUG administration; DRUG tablets; SOLID dosage forms; DRUG delivery systems; DRUG delivery devices
- Publication
Pharma Science Monitor, 2012, Vol 3, Issue 4, p3212
- ISSN
0976-9242
- Publication type
Article