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- Title
Introduction: Novel Aspects of the Germinal Center Reaction Special Issue.
- Authors
Kurosaki, Tomohiro
- Abstract
This article, published in the International Immunology journal, focuses on various aspects of the germinal center (GC) reaction and its role in humoral responses. The GC reaction is a complex process involving interactions between different cell types and affects B cell physiology and metabolism. The article discusses the development of phenotypic diversity and flexibility in generating protective antibody responses and immunological memory. It also covers topics such as memory B cell differentiation, immunometabolism, and the role of regulatory T cells in immune responses. The authors highlight the implications of these findings for vaccine design and potential therapeutic approaches for autoimmune diseases.
- Subjects
GERMINAL centers; IMMUNOLOGIC memory; B cell differentiation; REGULATORY T cells; B cells
- Publication
International Immunology, 2023, Vol 35, Issue 12, p561
- ISSN
0953-8178
- Publication type
Article
- DOI
10.1093/intimm/dxad040