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- Title
Oral submucous fibrosis: Etiology and management – A review.
- Authors
Devarajan, Harish; Somasundaram, Sujatha
- Abstract
Oral submucous fibrosis (OSF) is a premalignant condition caused by betel chewing. It is very common in Southeast Asia but has started to spread to Europe and North America. OSF can lead to squamous cell carcinoma, a risk that is further increased by concomitant tobacco consumption. OSF is a diagnosis based on clinical symptoms and confirmation by histopathology. Areca nut has been deeply rooted in Indian culture and been used as a mouth freshening agent that has had various symbolic roles throughout Indian history. Hypovascularity leading to blanching of the oral mucosa, staining of teeth and gingiva, and trismus are major symptoms. Prevention is most important, as no healing can be achieved with available treatments.
- Subjects
SOUTHEAST Asia; ORAL submucous fibrosis; ORAL mucosa; GINGIVA; BETEL nut; PRECANCEROUS conditions; ETIOLOGY of diseases; SQUAMOUS cell carcinoma
- Publication
Drug Invention Today, 2019, Vol 11, Issue 6, p1392
- ISSN
0975-7619
- Publication type
Article