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- Title
Assessments of individual fiber glycogen and mitochondrial volume percentages reveal a graded reduction in muscle oxidative power during prolonged exhaustive exercise.
- Authors
Nielsen, Joachim; Jensen, Rasmus; Ørtenblad, Niels
- Abstract
During submaximal exercise, there is a heterogeneous recruitment of skeletal muscle fibers, with an ensuing heterogeneous depletion of muscle glycogen both within and between fiber types. Here, we show that the mean (95% CI) mitochondrial volume as a percentage of fiber volume of non‐glycogen‐depleted fibers was 2 (−10:6), 5 (−21:11), and 12 (−21:−2)% lower than all the sampled fibers after continuing exercise for 1, 2 h, and until task failure, respectively. Therefore, a glycogen‐dependent fatigue of individual fibers during submaximal exercise may reduce the muscular oxidative power. These findings suggest a relationship between glycogen and mitochondrial content in individual muscle fibers, which is important for understanding fatigue during prolonged exercise.
- Subjects
SKELETAL muscle; CONFIDENCE intervals; EXERCISE physiology; MUSCLE fatigue; MITOCHONDRIA; OXIDATIVE stress; EXERCISE intensity; DESCRIPTIVE statistics; RESEARCH funding; GLYCOGEN
- Publication
Scandinavian Journal of Medicine & Science in Sports, 2024, Vol 34, Issue 2, p1
- ISSN
0905-7188
- Publication type
Article
- DOI
10.1111/sms.14571