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- Title
Comparative anti-glycation and α-glucosidase inhibition studies of microbial transformed compounds of dydrogesterone.
- Authors
Azizuddin; Rasheed, Saima; Naz, Shaista; Naheed, Suad; Choudhary, Muhammad Iqbal
- Abstract
Anti-glycation and a-glucosidase inhibition activities of microbial transformed compounds of dydrogesterone (1); 20R-hydroxy-9β,10α-pregna-4,6-diene-3-one (2), 17β-hydroxy-9β,10α-androsta-4,6-diene-3-one (3) and 9β, 10α-androsta-4,6-diene-3,17-dione (4) were evaluated. Compounds 1 and 4 showed potent α-glucosidase inhibitory activities, while 2 and 3 were found to be weak inhibitors, whereas anti-glycation activities of 1-4 were not observed.
- Subjects
COMPARATIVE studies; GLUCOSIDASE inhibitors; MICROBIOLOGICAL synthesis; DIOLEFINS; HYDROXY acids
- Publication
Pakistan Journal of Pharmaceutical Sciences, 2015, Vol 28, Issue 2, p521
- ISSN
1011-601X
- Publication type
Article