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- Title
Consolidation and Maintenance Immunotherapy With Rituximab Improve Clinical Outcome in Patients With B-cell Chronic Lymphocytic Leukemia.
- Authors
Del Poeta, Giovanni; Del Principe, Maria Ilaria; Buccisano, Francesco; Maurillo, Luca; Capelli, Giovanni; Luciano, Fabrizio; Perrotti, Alessio Pio; Degan, Massimo; Venditti, Adriano; De Fabritiis, Paolo; Gattei, Valter; Amadori, Sergio
- Abstract
The article focuses on a study which attempted to demonstrate whether consolidation/maintenance therapy with ritumixab could prolong the response duration in patients with B-cell chronic lymphocytic leukemia who were in complete remission (CR) or partial remission (PR) who were positive for minimal residual disease (MRD), as determined by flow cytometry. The study found that 61 of 75 patients achieved a CR, 10 of 75 patients had a PR and 4 of 75 patients had either no response or disease progression.
- Subjects
LYMPHOCYTIC leukemia; SPONTANEOUS cancer regression; DISEASE remission; LYMPHOPROLIFERATIVE disorders; CHRONIC lymphocytic leukemia treatment; LEUKEMIA treatment; THERAPEUTICS
- Publication
Cancer (0008543X), 2008, Vol 112, Issue 1, p119
- ISSN
0008-543X
- Publication type
Article
- DOI
10.1002/cncr.23144