We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Effect of Sarcopenia on Pneumonia after Endoscopic Submucosal Resection in Patients Aged ≥65 Years: A Retrospective Study.
- Authors
Kim, Min-Yu; Kim, So Yeon; Shin, Hye Jung; Kweon, Ki Hong; Park, Jooeun; Kim, Na Young
- Abstract
Simple Summary: Elderly patients have a higher risk of developing pneumonia due to a decrease in the swallowing function and the effectiveness of coughing. Sarcopenia is an age-related decrease in muscle mass and strength. We investigated the association between sarcopenia and incidence of pneumonia after endoscopic submucosal dissection (ESD) in patients aged ≥65 years. Patients with (n = 1571) and without sarcopenia (n = 1718) who underwent ESD for gastric neoplasm were included. Propensity score matching (PSM) was performed between the groups at a 1:1 ratio. The primary endpoint was the effect of sarcopenia on the incidence of pneumonia after ESD. Patients with sarcopenia had an increased risk of developing pneumonia after ESD, even after adjusting for other factors, resulting in a higher incidence of leukocytosis and a longer duration of post-ESD hospitalization. The combination of sarcopenia and age ≥73 years could be an effective predictive factor for screening high-risk groups for pneumonia after ESD. We aimed to investigate the association between sarcopenia and incidence of pneumonia after endoscopic submucosal dissection (ESD) in patients aged ≥65 years. Patients with (n = 1571) and without sarcopenia (n = 1718) who underwent ESD for gastric neoplasm were included. Propensity score matching (PSM) was performed between the groups (n = 785) at a 1:1 ratio. The primary endpoint was the effect of sarcopenia on the incidence of pneumonia after ESD. Among the included patients, 2.2% (n = 71) developed pneumonia after ESD. After PSM, the incidence rate of pneumonia was significantly higher in patients with sarcopenia than that in patients without sarcopenia (p = 0.024). Sarcopenia and age ≥73 years were significantly associated with the incidence of pneumonia (sarcopenia and age <73 years, odd ratio (OR) = 1.22 [95% confidence interval (CI): 0.46–3.22]; sarcopenia and age ≥73 years, OR = 3.92 [95% CI: 1.79–8.74]). Patients with sarcopenia had an increased risk of developing pneumonia after ESD, even after adjusting for other factors, resulting in a higher incidence of leukocytosis and a longer duration of post-ESD hospitalization. The combination of sarcopenia and age ≥73 years could be an effective predictive factor for screening high-risk groups for pneumonia after ESD.
- Subjects
RISK factors of pneumonia; LENGTH of stay in hospitals; CONFIDENCE intervals; ANESTHESIA; SARCOPENIA; SURGICAL complications; RETROSPECTIVE studies; GASTROINTESTINAL tumors; DESCRIPTIVE statistics; RESEARCH funding; ENDOSCOPIC gastrointestinal surgery; DATA analysis software; ODDS ratio
- Publication
Cancers, 2023, Vol 15, Issue 19, p4753
- ISSN
2072-6694
- Publication type
Article
- DOI
10.3390/cancers15194753