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Type 2 Diabetes Partitioned Polygenic Scores Associate With Disease Outcomes in 454,193 Individuals Across 13 Cohorts.
Published in:
2022
By:
- DiCorpo, Daniel;
- LeClair, Jessica;
- Cole, Joanne B.;
- Sarnowski, Chloé;
- Ahmadizar, Fariba;
- Bielak, Lawrence F.;
- Blokstra, Anneke;
- Bottinger, Erwin P.;
- Chaker, Layal;
- Chen, Yii-Der I.;
- Chen, Ye;
- de Vries, Paul S.;
- Faquih, Tariq;
- Ghanbari, Mohsen;
- Gudmundsdottir, Valborg;
- Guo, Xiuqing;
- Hasbani, Natalie R.;
- Ibi, Dorina;
- Ikram, M. Arfan;
- Kavousi, Maryam
Publication type:
journal article
Arsenic exposure is associated with diminished insulin sensitivity in non-diabetic Amish adults.
Published in:
2016
By:
- Park, Sung Kyun;
- Peng, Qing;
- Bielak, Lawrence F.;
- Silver, Kristi D.;
- Peyser, Patricia A.;
- Mitchell, Braxton D.
Publication type:
journal article
Gender- and age-dependent relationships between the E-selectin S128R polymorphism and coronary artery calcification.
Published in:
Journal of Molecular Medicine, 2001, v. 79, n. 7, p. 390, doi. 10.1007/s001090100235
By:
- Ellsworth, Darrell L.;
- Bielak, Lawrence F.;
- Turner, Stephen T.;
- Sheedy, Patrick F.;
- Boerwinkle, Eric;
- Peyser, Patricia A.
Publication type:
Article
Potential of Quantity of Coronary Artery Calcification to Identify New Risk Factors for Asymptomatic Atherosclerosis.
Published in:
American Journal of Epidemiology, 1996, v. 144, n. 10, p. 943, doi. 10.1093/oxfordjournals.aje.a008864
By:
- Maher, Julie E.;
- Raz, Jonathan A.;
- Bielak, Lawrence F.;
- Sheecly, Patrick F.;
- Schwartz, Robert S.;
- Peyser, Patricia A.
Publication type:
Article
Multivariate, region‐based genetic analyses of facets of reproductive aging in White and Black women.
Published in:
Molecular Genetics & Genomic Medicine, 2022, v. 10, n. 4, p. 1, doi. 10.1002/mgg3.1896
By:
- Bielak, Lawrence F.;
- Peyser, Patricia A.;
- Smith, Jennifer A.;
- Zhao, Wei;
- Ruiz‐Narvaez, Edward A.;
- Kardia, Sharon L. R.;
- Harlow, Sioban D.
Publication type:
Article
Association Between Whole Blood-Derived Mitochondrial DNA Copy Number, Low-Density Lipoprotein Cholesterol, and Cardiovascular Disease Risk.
Published in:
Journal of the American Heart Association, 2023, v. 12, n. 20, p. 1, doi. 10.1161/JAHA.122.029090
By:
- Xue Liu;
- Xianbang Sun;
- Yuankai Zhang;
- Wenqing Jiang;
- Meng Lai;
- Wiggins, Kerri L.;
- Raffield, Laura M.;
- Bielak, Lawrence F.;
- Wei Zhao;
- Pitsillides, Achilleas;
- Haessler, Jeffrey;
- Yinan Zheng;
- Blackwell, Thomas W.;
- Jie Yao;
- Xiuqing Guo;
- Yong Qian;
- Thyagarajan, Bharat;
- Pankratz, Nathan;
- Rich, Stephen S.;
- Taylor, Kent D.
Publication type:
Article
Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci.
Published in:
Frontiers in Genetics, 2023, p. 1, doi. 10.3389/fgene.2023.1235337
By:
- de las Fuentes, Lisa;
- Schwander, Karen L.;
- Brown, Michael R.;
- Bentley, Amy R.;
- Winkler, Thomas W.;
- Yun Ju Sung;
- Munroe, Patricia B.;
- Miller, Clint L.;
- Hugo Aschard;
- Aslibekyan, Stella;
- Bartz, Traci M.;
- Bielak, Lawrence F.;
- Jin Fang Chai;
- Ching-Yu Cheng;
- Dorajoo, Rajkumar;
- Feitosa, Mary F.;
- Xiuqing Guo;
- Hartwig, Fernando P.;
- Horimoto, Andrea;
- Kolčić, Ivana
Publication type:
Article
Smoking-by-genotype interaction in type 2 diabetes risk and fasting glucose.
Published in:
PLoS ONE, 2020, v. 15, n. 5, p. 1, doi. 10.1371/journal.pone.0230815
By:
- Wu, Peitao;
- Rybin, Denis;
- Bielak, Lawrence F.;
- Feitosa, Mary F.;
- Franceschini, Nora;
- Li, Yize;
- Lu, Yingchang;
- Marten, Jonathan;
- Musani, Solomon K.;
- Noordam, Raymond;
- Raghavan, Sridharan;
- Rose, Lynda M.;
- Schwander, Karen;
- Smith, Albert V.;
- Tajuddin, Salman M.;
- Vojinovic, Dina;
- Amin, Najaf;
- Arnett, Donna K.;
- Bottinger, Erwin P.;
- Demirkan, Ayse
Publication type:
Article
A Noncoding Variant Near PPP1R3B Promotes Liver Glycogen Storage and MetS, but Protects Against Myocardial Infarction.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2021, v. 106, n. 2, p. 372, doi. 10.1210/clinem/dgaa855
By:
- Kahali, Bratati;
- Yue Chen;
- Feitosa, Mary F.;
- Bielak, Lawrence F.;
- O’Connell, Jeffrey R.;
- Musani, Solomon K.;
- Hegde, Yash;
- Yanhua Chen;
- Stetson, L. C.;
- Xiuqing Guo;
- Yi-ping Fu;
- Vernon Smith, Albert;
- Ryan, Kathleen A.;
- Eiriksdottir, Gudny;
- Cohain, Ariella T.;
- Allison, Matthew;
- Bakshi, Andrew;
- Bowden, Donald W.;
- Budoff, Matthew J.;
- Carr, J. Jeffrey
Publication type:
Article
Testing cross-phenotype effects of rare variants in longitudinal studies of complex traits.
Published in:
Genetic Epidemiology, 2018, v. 42, n. 4, p. 320, doi. 10.1002/gepi.22121
By:
- Rudra, Pratyaydipta;
- Broadaway, K. Alaine;
- Ware, Erin B.;
- Jhun, Min A.;
- Bielak, Lawrence F.;
- Zhao, Wei;
- Smith, Jennifer A.;
- Peyser, Patricia A.;
- Kardia, Sharon L.R.;
- Epstein, Michael P.;
- Ghosh, Debashis
Publication type:
Article
SNP Set Association Analysis for Familial Data.
Published in:
Genetic Epidemiology, 2012, v. 36, n. 8, p. 797, doi. 10.1002/gepi.21676
By:
- Schifano, Elizabeth D.;
- Epstein, Michael P.;
- Bielak, Lawrence F.;
- Jhun, Min A.;
- Kardia, Sharon L. R.;
- Peyser, Patricia A.;
- Lin, Xihong
Publication type:
Article
Application of machine learning algorithms to predict coronary artery calcification with a sibship-based design.
Published in:
Genetic Epidemiology, 2008, v. 32, n. 4, p. 350, doi. 10.1002/gepi.20309
By:
- Sun, Yan V.;
- Bielak, Lawrence F.;
- Peyser, Patricia A.;
- Turner, Stephen T.;
- Sheedy, Patrick F.;
- Boerwinkle, Eric;
- Kardia, Sharon L.R.
Publication type:
Article
Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-22339-1
By:
- Natarajan, Pradeep;
- Pampana, Akhil;
- Graham, Sarah E.;
- Ruotsalainen, Sanni E.;
- Perry, James A.;
- de Vries, Paul S.;
- Broome, Jai G.;
- Pirruccello, James P.;
- Honigberg, Michael C.;
- Aragam, Krishna;
- Wolford, Brooke;
- Brody, Jennifer A.;
- Antonacci-Fulton, Lucinda;
- Arden, Moscati;
- Aslibekyan, Stella;
- Assimes, Themistocles L.;
- Ballantyne, Christie M.;
- Bielak, Lawrence F.;
- Bis, Joshua C.;
- Cade, Brian E.
Publication type:
Article
Genome-wide association study of serum liver enzymes implicates diverse metabolic and liver pathology.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-020-20870-1
By:
- Chen, Vincent L.;
- Du, Xiaomeng;
- Chen, Yanhua;
- Kuppa, Annapurna;
- Handelman, Samuel K.;
- Vohnoutka, Rishel B.;
- Peyser, Patricia A.;
- Palmer, Nicholette D.;
- Bielak, Lawrence F.;
- Halligan, Brian;
- Speliotes, Elizabeth K.
Publication type:
Article
Prospective associations between beverage intake during the midlife and subclinical carotid atherosclerosis: The Study of Women’s Health Across the Nation.
Published in:
PLoS ONE, 2019, v. 14, n. 7, p. 1, doi. 10.1371/journal.pone.0219301
By:
- Wang, Dongqing;
- Karvonen-Gutierrez, Carrie A.;
- Jackson, Elizabeth A.;
- Elliott, Michael R.;
- Appelhans, Bradley M.;
- Barinas-Mitchell, Emma;
- Bielak, Lawrence F.;
- Baylin, Ana
Publication type:
Article
Mendelian randomization evaluation of causal effects of fibrinogen on incident coronary heart disease.
Published in:
PLoS ONE, 2019, v. 14, n. 5, p. 1, doi. 10.1371/journal.pone.0216222
By:
- Ward-Caviness, Cavin K.;
- de Vries, Paul S.;
- Wiggins, Kerri L.;
- Huffman, Jennifer E.;
- Yanek, Lisa R.;
- Bielak, Lawrence F.;
- Giulianini, Franco;
- Guo, Xiuqing;
- Kleber, Marcus E.;
- Kacprowski, Tim;
- Groß, Stefan;
- Petersman, Astrid;
- Davey Smith, George;
- Hartwig, Fernando P.;
- Bowden, Jack;
- Hemani, Gibran;
- Müller-Nuraysid, Martina;
- Strauch, Konstantin;
- Koenig, Wolfgang;
- Waldenberger, Melanie
Publication type:
Article
Associations of Serum Uric Acid With Markers of Inflammation, Metabolic Syndrome, and Subclinical Coronary Atherosclerosis
Published in:
American Journal of Hypertension, 2007, v. 20, n. 1, p. 83, doi. 10.1016/j.amjhyper.2006.06.015
By:
- Coutinho, Thais de A.;
- Turner, Stephen T.;
- Peyser, Patricia A.;
- Bielak, Lawrence F.;
- Sheedy, Patrick F.;
- Kullo, Iftikhar J.
Publication type:
Article
C-Reactive Protein Is Related to Arterial Wave Reflection and Stiffness in Asymptomatic Subjects From the Community
Published in:
American Journal of Hypertension, 2005, v. 18, n. 8, p. 1123, doi. 10.1016/j.amjhyper.2005.03.730
By:
- Kullo, Iftikhar J.;
- Seward, James B.;
- Bailey, Kent R.;
- Bielak, Lawrence F.;
- Grossardt, Brandon R.;
- Sheedy, Patrick F.;
- Peyser, Patricia A.;
- Turner, Stephen T.
Publication type:
Article
Low-density lipoprotein particle size and coronary atherosclerosis in subjects belonging to hypertensive sibships
Published in:
American Journal of Hypertension, 2004, v. 17, n. 9, p. 845, doi. 10.1016/j.amjhyper.2004.06.012
By:
- Kullo, Iftikhar J.;
- Bailey, Kent R.;
- McConnell, Joseph P.;
- Peyser, Patricia A.;
- Bielak, Lawrence F.;
- Kardia, Sharon L.R.;
- Sheedy, Patrick F.;
- Boerwinkle, Eric;
- Turner, Stephen T.
Publication type:
Article
Ambulatory blood pressure and coronary artery calcification in middle-aged and younger adults.
Published in:
American Journal of Hypertension, 2002, v. 15, n. 6, p. 518, doi. 10.1016/S0895-7061(02)02271-9
By:
- Turner, Stephen T.;
- Bielak, Lawrence F.;
- Narayana, Arvind K.;
- Sheedy II, Patrick F.;
- Schwartz, Gary L.;
- Peyser, Patricia A.
Publication type:
Article
Neighborhood-Level Poverty at Menarche and Prepregnancy Obesity in African-American Women.
Published in:
Journal of Pregnancy, 2016, p. 1, doi. 10.1155/2016/4769121
By:
- Cassidy-Bushrow, Andrea E.;
- Peters, Rosalind M.;
- Burmeister, Charlotte;
- Bielak, Lawrence F.;
- Johnson, Dayna A.
Publication type:
Article
Genome-Wide Association Study of Gene by Smoking Interactions in Coronary Artery Calcification.
Published in:
PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0074642
By:
- Polfus, Linda M.;
- Smith, Jennifer A.;
- Shimmin, Lawrence C.;
- Bielak, Lawrence F.;
- Morrison, Alanna C.;
- Kardia, Sharon L. R.;
- Peyser, Patricia A.;
- Hixson, James E.
Publication type:
Article
Author Correction: Genome-wide association study of serum liver enzymes implicates diverse metabolic and liver pathology.
Published in:
2023
By:
- Chen, Vincent L.;
- Du, Xiaomeng;
- Chen, Yanhua;
- Kuppa, Annapurna;
- Handelman, Samuel K.;
- Vohnoutka, Rishel B.;
- Peyser, Patricia A.;
- Palmer, Nicholette D.;
- Bielak, Lawrence F.;
- Halligan, Brian;
- Speliotes, Elizabeth K.
Publication type:
Correction Notice
A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.
Published in:
Nature Genetics, 2013, v. 45, n. 6, p. 690, doi. 10.1038/ng.2608
By:
- Monda, Keri L;
- Chen, Gary K;
- Taylor, Kira C;
- Palmer, Cameron;
- Edwards, Todd L;
- Lange, Leslie A;
- Ng, Maggie C Y;
- Adeyemo, Adebowale A;
- Allison, Matthew A;
- Bielak, Lawrence F;
- Chen, Guanjie;
- Graff, Mariaelisa;
- Irvin, Marguerite R;
- Rhie, Suhn K;
- Li, Guo;
- Liu, Yongmei;
- Liu, Youfang;
- Lu, Yingchang;
- Nalls, Michael A;
- Sun, Yan V
Publication type:
Article
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.
Published in:
Nature Genetics, 2012, v. 44, n. 6, p. 659, doi. 10.1038/ng.2274
By:
- Manning, Alisa K;
- Hivert, Marie-France;
- Scott, Robert A;
- Grimsby, Jonna L;
- Bouatia-Naji, Nabila;
- Chen, Han;
- Rybin, Denis;
- Liu, Ching-Ti;
- Bielak, Lawrence F;
- Prokopenko, Inga;
- Amin, Najaf;
- Barnes, Daniel;
- Cadby, Gemma;
- Hottenga, Jouke-Jan;
- Ingelsson, Erik;
- Jackson, Anne U;
- Johnson, Toby;
- Kanoni, Stavroula;
- Ladenvall, Claes;
- Lagou, Vasiliki
Publication type:
Article
Breast Arterial Calcification Is Associated with Reproductive Factors in Asymptomatic Postmenopausal Women.
Published in:
Journal of Women's Health (15409996), 2010, v. 19, n. 9, p. 1721, doi. 10.1089/jwh.2010.1932
By:
- Bielak, Lawrence F.;
- Whaley, Dana H.;
- Sheedy, Patrick F.;
- Peyser, Patricia A.
Publication type:
Article
Hypertension during Pregnancy is Associated with Coronary Artery Calcium Independent of Renal Function.
Published in:
Journal of Women's Health (15409996), 2009, v. 18, n. 10, p. 1709, doi. 10.1089/jwh.2008.1285
By:
- Cassidy-Bushrow, Andrea E.;
- Bielak, Lawrence F.;
- Rule, Andrew D.;
- Sheedy, Patrick F.;
- Turner, Stephen T.;
- Garovic, Vesna D.;
- Peyser, Patricia A.
Publication type:
Article
Serum 25-hydroxyvitamin d levels are not associated with subclinical vascular disease or C-reactive protein in the old order amish.
Published in:
2009
By:
- Michos, Erin D.;
- Streeten, Elizabeth A.;
- Ryan, Kathleen;
- Rampersaud, Evadnie;
- Peyser, Patricia A.;
- Bielak, Lawrence F.;
- Shuldiner, Alan R.;
- Mitchell, Braxton D.;
- Post, Wendy;
- Ryan, Kathleen A
Publication type:
journal article
Relationships of Clinical and Computed Tomography-Imaged Adiposity with Cognition in Middle-Aged and Older African Americans.
Published in:
2018
By:
- Parker, Kirby G.;
- Lirette, Seth T.;
- Deardorff, David S.;
- Bielak, Lawrence F.;
- Peyser, Patricia A.;
- Carr, J. Jeffrey;
- Terry, James G.;
- Fornage, Myriam;
- Benjamin, Emelia J.;
- Turner, Stephen T.;
- Mosley, Thomas H.;
- Griswold, Michael E.;
- Windham, B. Gwen
Publication type:
journal article
Circulating CD34+ Cell Count is Associated with Extent of Subclinical Atherosclerosis in Asymptomatic Amish Men, Independent of 10-Year Framingham Risk.
Published in:
Clinical Medicine: Cardiology, 2009, v. 3, p. 53, doi. 10.4137/CMC.S2111
By:
- Bielak, Lawrence F.;
- Horenstein, Richard B.;
- Ryan, Kathleen A.;
- Sheedy II, Patrick F.;
- Rumberger, John A.;
- Tanner, Keith;
- Post, Wendy;
- Mitchell, Braxton D.;
- Shuldiner, Alan R.;
- Peyser, Patricia A.
Publication type:
Article
The Association of Coronary Artery Calcification and Carotid Artery Intima-Media Thickness With Distinct, Traditional Coronary Artery Disease Risk Factors in Asymptomatic Adults.
Published in:
American Journal of Epidemiology, 2008, v. 168, n. 9, p. 1016, doi. 10.1093/aje/kwn211
By:
- Evadnie Rampersaud;
- Lawrence F. Bielak;
- Afshin Parsa;
- Haiqing Shen;
- Wendy Post;
- Kathleen A. Ryan;
- Patrick Donnelly;
- John A. Rumberger;
- Patrick F. Sheedy;
- Patricia A. Peyser;
- Alan R. Shuldiner;
- Braxton D. Mitchell
Publication type:
Article
The relationship between diastolic blood pressure and coronary artery calcification is dependent on single nucleotide polymorphisms on chromosome 9p21.3.
Published in:
BMC Medical Genetics, 2014, v. 15, n. 1, p. 1, doi. 10.1186/s12881-014-0089-2
By:
- Kim, Daniel S.;
- Smith, Jennifer A.;
- Bielak, Lawrence F.;
- Chun-Yi Wu;
- Yan Sun;
- Sheedy II, Patrick F.;
- Turner, Stephen T.;
- Peyser, Patricia A.;
- Kardia, Sharon L. R.
Publication type:
Article
Genetics of coronary artery calcification among African Americans, a meta-analysis.
Published in:
BMC Medical Genetics, 2013, v. 14, n. 1, p. 1, doi. 10.1186/1471-2350-14-75
By:
- Wojczynski, Mary K.;
- Li, Mingyao;
- Bielak, Lawrence F.;
- Kerr, Kathleen F.;
- Reiner, Alex P.;
- Wong, Nathan D.;
- Yanek, Lisa R.;
- Qu, Liming;
- White, Charles C.;
- Lange, Leslie A.;
- Ferguson, Jane F.;
- He, Jing;
- Young, Taylor;
- Mosley, Thomas H.;
- Smith, Jennifer A.;
- Kral, Brian G.;
- Guo, Xiuqing;
- Wong, Quenna;
- Ganesh, Santhi K.;
- Heckbert, Susan R.
Publication type:
Article
Rare coding variants in RCN3 are associated with blood pressure.
Published in:
BMC Genomics, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s12864-022-08356-4
By:
- He, Karen Y.;
- Kelly, Tanika N.;
- Wang, Heming;
- Liang, Jingjing;
- Zhu, Luke;
- Cade, Brian E.;
- Assimes, Themistocles L.;
- Becker, Lewis C.;
- Beitelshees, Amber L.;
- Bielak, Lawrence F.;
- Bress, Adam P.;
- Brody, Jennifer A.;
- Chang, Yen-Pei Christy;
- Chang, Yi-Cheng;
- de Vries, Paul S.;
- Duggirala, Ravindranath;
- Fox, Ervin R.;
- Franceschini, Nora;
- Furniss, Anna L.;
- Gao, Yan
Publication type:
Article
Epigenome-wide association study of mitochondrial genome copy number.
Published in:
Human Molecular Genetics, 2022, v. 31, n. 2, p. 309, doi. 10.1093/hmg/ddab240
By:
- Wang, Penglong;
- Castellani, Christina A;
- Yao, Jie;
- Huan, Tianxiao;
- Bielak, Lawrence F;
- Zhao, Wei;
- Haessler, Jeffrey;
- Joehanes, Roby;
- Sun, Xianbang;
- Guo, Xiuqing;
- Longchamps, Ryan J;
- Manson, JoAnn E;
- Grove, Megan L;
- Bressler, Jan;
- Taylor, Kent D;
- Lappalainen, Tuuli;
- Kasela, Silva;
- Berg, David J Van Den;
- Hou, Lifang;
- Reiner, Alexander
Publication type:
Article
Allele-specific variation at APOE increases nonalcoholic fatty liver disease and obesity but decreases risk of Alzheimer's disease and myocardial infarction.
Published in:
Human Molecular Genetics, 2021, v. 30, n. 15, p. 1443, doi. 10.1093/hmg/ddab096
By:
- Palmer, Nicholette D;
- Kahali, Bratati;
- Kuppa, Annapurna;
- Chen, Yanhua;
- Du, Xiaomeng;
- Feitosa, Mary F;
- Bielak, Lawrence F;
- O'Connell, Jeffrey R;
- Musani, Solomon K;
- Guo, Xiuqing;
- Smith, Albert V;
- Ryan, Kathleen A;
- Eirksdottir, Gudny;
- Allison, Matthew A;
- Bowden, Donald W;
- Budoff, Matthew J;
- Carr, J Jeffrey;
- Chen, Yii-Der I;
- Taylor, Kent D;
- Correa, Adolfo
Publication type:
Article
Epigenetics of single-site and multi-site atherosclerosis in African Americans from the Genetic Epidemiology Network of Arteriopathy (GENOA).
Published in:
Clinical Epigenetics, 2022, v. 14, n. 1, p. 1, doi. 10.1186/s13148-022-01229-3
By:
- Ammous, Farah;
- Zhao, Wei;
- Lin, Lisha;
- Ratliff, Scott M.;
- Mosley, Thomas H.;
- Bielak, Lawrence F.;
- Zhou, Xiang;
- Peyser, Patricia A.;
- Kardia, Sharon L. R.;
- Smith, Jennifer A.
Publication type:
Article
Epigenetic age acceleration is associated with cardiometabolic risk factors and clinical cardiovascular disease risk scores in African Americans.
Published in:
Clinical Epigenetics, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13148-021-01035-3
By:
- Ammous, Farah;
- Zhao, Wei;
- Ratliff, Scott M.;
- Mosley, Thomas H.;
- Bielak, Lawrence F.;
- Zhou, Xiang;
- Peyser, Patricia A.;
- Kardia, Sharon L. R.;
- Smith, Jennifer A.
Publication type:
Article

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