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- Title
An Overview of Pediatric Uveitis.
- Authors
Tuğal-Tutkun, İlknur
- Abstract
Uveitis in childhood poses a distinct challenge, mainly because of the insidious onset and chronic course of intraocular inflammation in most cases, which may result in permanent visual loss due to delayed diagnosis and treatment. Although anterior uveitis, frequently associated with juvenile idiopathic arthritis, is the most common form of ocular involvement, idiopathic intermediate uveitis (pars planitis) is also a common uveitic entity in childhood. Posterior or panuveitis of a variety of noninfectious or infectious etiologies may be seen as well. Pediatric uveitis needs to be closely monitored since serious ocular complications such as intraocular pressure elevation, cataract, and macular edema may rapidly develop due to inadequately controlled inflammation and/or the use of corticosteroids. Methotrexate is generally the firstline corticosteroid-sparing agent, and adalimumab is the first-line biologic in refractory cases of noninfectious uveitis. A multidisciplinary approach is essential to monitor systemic disease associations, treatment response, and adverse events in children with uveitis.
- Subjects
UVEITIS treatment; BLINDNESS; INFLAMMATION; SLIT lamp microscopy; UVEITIS; TREATMENT effectiveness; METHOTREXATE; HEALTH care teams; OPTICAL coherence tomography; ADALIMUMAB; IRIDOCYCLITIS; EYE diseases; DISEASE risk factors; DISEASE complications; CHILDREN
- Publication
Turkish Archives of Pediatrics, 2023, Vol 58, Issue 4, p363
- ISSN
2757-6256
- Publication type
Article
- DOI
10.5152/TurkArchPediatr.2023.23086