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- Title
Effects of Physical Activity and Nutrition Education on the Gut Microbiota in Overweight and Obese Children.
- Authors
Morgado, Micaela C.; Sousa, Mónica; Marques, Cláudia; Coelho, André B.; Costa, Júlio A.; Seabra, André
- Abstract
Childhood obesity continues to represent a growing challenge, and it has been associated with gut microbiota dysbiosis. This study examines the gut microbiota composition in overweight and obese school children and assesses whether a 12-week multidisciplinary intervention can induce changes in the gut microbiota. The intervention, which combined recreational football and nutritional education, was implemented among 15 school children, aged 7–10 years, with a Body Mass Index ≥ 85th percentile. The children were assigned into two groups: Football Group (n = 9) and Nutrition and Football Group (n = 6). Faecal samples were collected at the beginning and end of the program and analysed by sequencing the 16S rRNA gene. Over the intervention, a significant decrease was found collectively for Bifidobacterium genera (p = 0.011) and for Roseburia genera in the Football Group (p = 0.021). The relative abundance of Roseburia (p = 0.002) and Roseburia faecis (p = 0.009) was negatively correlated with moderate to vigorous physical activity (MVPA), while Prevotella copri was positively correlated with MVPA (p = 0.010) and with the daily intake of protein (p = 0.008). Our findings suggest that a multidisciplinary intervention was capable of inducing limited but significant positive changes in the gut microbiota composition in overweight and obese school children.
- Subjects
RESEARCH funding; RECREATION; SOCCER; BODY mass index; DATA analysis; GUT microbiome; TREATMENT effectiveness; MANN Whitney U Test; DESCRIPTIVE statistics; RNA; GENES; STATISTICS; CHILDHOOD obesity; DATA analysis software; PHYSICAL activity; NUTRITION education; SCHOOL health services; HEALTH care teams
- Publication
Children, 2023, Vol 10, Issue 7, p1242
- ISSN
2227-9067
- Publication type
Article
- DOI
10.3390/children10071242