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The genomic landscape of oesophagogastric junctional adenocarcinoma.
Published in:
Journal of Pathology, 2013, v. 231, n. 3, p. 301, doi. 10.1002/path.4247
By:
- Chong, Irene Y;
- Cunningham, David;
- Barber, Louise J;
- Campbell, James;
- Chen, Lina;
- Kozarewa, Iwanka;
- Fenwick, Kerry;
- Assiotis, Ioannis;
- Guettler, Sebastian;
- Garcia‐Murillas, Isaac;
- Awan, Saima;
- Lambros, Maryou;
- Starling, Naureen;
- Wotherspoon, Andrew;
- Stamp, Gordon;
- Gonzalez‐de‐Castro, David;
- Benson, Martin;
- Chau, Ian;
- Hulkki, Sanna;
- Nohadani, Mahrokh
Publication type:
Article
Cellular apoptosis susceptibility (chromosome segregation 1-like, CSE1L) gene is a key regulator of apoptosis, migration and invasion in colorectal cancer.
Published in:
Journal of Pathology, 2012, v. 228, n. 4, p. 471, doi. 10.1002/path.4031
By:
- Alnabulsi, Ayham;
- Agouni, Abdelali;
- Mitra, Suman;
- Garcia-Murillas, Isaac;
- Carpenter, Brian;
- Bird, Steve;
- Murray, Graeme I
Publication type:
Article
Efficient Genotyping of KRAS Mutant Non-Small Cell Lung Cancer Using a Multiplexed Droplet Digital PCR Approach.
Published in:
PLoS ONE, 2015, v. 10, n. 9, p. 1, doi. 10.1371/journal.pone.0139074
By:
- Pender, Alexandra;
- Garcia-Murillas, Isaac;
- Rana, Sareena;
- Cutts, Rosalind J.;
- Kelly, Gavin;
- Fenwick, Kerry;
- Kozarewa, Iwanka;
- Gonzalez de Castro, David;
- Bhosle, Jaishree;
- O’Brien, Mary;
- Turner, Nicholas C.;
- Popat, Sanjay;
- Downward, Julian
Publication type:
Article
Determination of <i>HER2</i> Amplification Status on Tumour DNA by Digital PCR.
Published in:
PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0083409
By:
- Garcia-Murillas, Isaac;
- Lambros, Maryou;
- Turner, Nicholas C.
Publication type:
Article
Circulating HPV DNA as a Biomarker for Pre-Invasive and Early Invasive Cervical Cancer: A Feasibility Study.
Published in:
Cancers, 2023, v. 15, n. 9, p. 2590, doi. 10.3390/cancers15092590
By:
- Bryan, Stacey J.;
- Lee, Jen;
- Gunu, Richard;
- Jones, Allison;
- Olaitan, Adeola;
- Rosenthal, Adam N.;
- Cutts, Ros J.;
- Garcia-Murillas, Isaac;
- Turner, Nick;
- Lalondrelle, Susan;
- Bhide, Shreerang A.
Publication type:
Article
Predicting Response to Radical Chemoradiotherapy with Circulating HPV DNA (cHPV-DNA) in Locally Advanced Uterine Cervix Cancer.
Published in:
Cancers, 2023, v. 15, n. 5, p. 1387, doi. 10.3390/cancers15051387
By:
- Lalondrelle, Susan;
- Lee, Jen;
- Cutts, Rosalind J.;
- Garcia Murillas, Isaac;
- Matthews, Nik;
- Turner, Nicholas;
- Harrington, Kevin;
- Vroobel, Katherine;
- Moretti, Emily;
- Bhide, Shreerang A.
Publication type:
Article
Relationship of PIK3CA mutation and pathway activity with anti-proliferative response to aromatase inhibition.
Published in:
Breast Cancer Research, 2014, v. 16, n. 3, p. 1, doi. 10.1186/bcr3683
By:
- López-Knowles, Elena;
- Segal, Corrinne V.;
- Qiong Gao;
- Garcia-Murillas, Isaac;
- Turner, Nicholas C.;
- Smith, Ian;
- Martin, Lesley-Ann;
- Dowsett, Mitch
Publication type:
Article
Relationship of PIK3CA mutation and pathway activity with antiproliferative response to aromatase inhibition.
Published in:
2014
By:
- López-Knowles, Elena;
- Segal, Corrinne V;
- Gao, Qiong;
- Garcia-Murillas, Isaac;
- Turner, Nicholas C;
- Smith, Ian;
- Martin, Lesley-Ann;
- Dowsett, Mitch
Publication type:
journal article
Comparison of BEAMing and Droplet Digital PCR for Circulating Tumor DNA Analysis.
Published in:
Clinical Chemistry, 2019, v. 65, n. 11, p. 1405, doi. 10.1373/clinchem.2019.305805
By:
- O’Leary, Ben;
- Hrebien, Sarah;
- Beaney, Matthew;
- Fribbens, Charlotte;
- Garcia-Murillas, Isaac;
- Jiang, John;
- Li, Yuan;
- Bartlett, Cynthia Huang;
- Andre´, Fabrice;
- Loibl, Sibylle;
- Loi, Sherene;
- Cristofanilli, Massimo;
- Turner, Nicholas C.
Publication type:
Article
Analysis of ESR1 mutation in circulating tumor DNA demonstrates evolution during therapy for metastatic breast cancer.
Published in:
Science Translational Medicine, 2015, v. 7, n. 313, p. 1, doi. 10.1126/scitranslmed.aac7551
By:
- Schiavon, Gaia;
- Hrebien, Sarah;
- Garcia-Murillas, Isaac;
- Cutts, Rosalind J.;
- Pearson, Alex;
- Tarazona, Noelia;
- Fenwick, Kerry;
- Iwanka Kozarewa;
- Lopez-Knowles, Elena;
- Ribas, Ricardo;
- Nerurkar, Ashutosh;
- Osin, Peter;
- Chandarlapaty, Sarat;
- Martin, Lesley-Ann;
- Dowsett, Mitch;
- Smith, Ian E.;
- Turner, Nicholas C.
Publication type:
Article
Mutation tracking in circulating tumor DNA predicts relapse in early breast cancer.
Published in:
Science Translational Medicine, 2015, v. 7, n. 302, p. 1, doi. 10.1126/scitranslmed.aab0021
By:
- Garcia-Murillas, Isaac;
- Schiavon, Gaia;
- Weigelt, Britta;
- Ng, Charlotte;
- Hrebien, Sarah;
- Cutts, Rosalind J.;
- Cheang, Maggie;
- Osin, Peter;
- Nerurkar, Ashutosh;
- Kozarewa, Iwanka;
- Garrido, Javier Armisen;
- Dowsett, Mitch;
- Reis-Filho, Jorge S.;
- Smith, Ian E.;
- Turner, Nicholas C.
Publication type:
Article
Molecular characterisation of aromatase inhibitor-resistant advanced breast cancer: the phenotypic effect of ESR1 mutations.
Published in:
2019
By:
- Lopez-Knowles, Elena;
- Pearson, Alex;
- Schuster, Gene;
- Gellert, Pascal;
- Ribas, Ricardo;
- Yeo, Belinda;
- Cutts, Ros;
- Buus, Richard;
- Garcia-Murillas, Isaac;
- Haynes, Ben;
- Martin, Lesley-Ann;
- Smith, Ian;
- Turner, Nick;
- Dowsett, Mitch
Publication type:
journal article
Predicting response to radical (chemo)radiotherapy with circulating HPV DNA in locally advanced head and neck squamous carcinoma.
Published in:
2017
By:
- Lee, Jen Y;
- Garcia-Murillas, Isaac;
- Cutts, Rosalind J;
- De Castro, David Gonzalez;
- Grove, Lorna;
- Hurley, Tara;
- Wang, Fuqiang;
- Nutting, Christopher;
- Newbold, Katie;
- Harrington, Kevin;
- Turner, Nicholas;
- Bhide, Shreerang
Publication type:
journal article
Rhabdomere biogenesis in Drosophila photoreceptors is acutely sensitive to phosphatidic acid levels.
Published in:
Journal of Cell Biology, 2009, v. 185, n. 1, p. 129, doi. 10.1083/jcb.200807027
By:
- Raghu, Padinjat;
- Coessens, Elise;
- Manifava, Maria;
- Georgiev, Plamen;
- Pettitt, Trevor;
- Wood, Eleanor;
- Garcia-Murillas, Isaac;
- Okkenhaug, Hanneke;
- Trivedi, Deepti;
- Qifeng Zhang;
- Razzaq, Azam;
- Zaid, Ola;
- Wakelam, Michael;
- O'Kane, Cahir J.;
- Ktistakis, Nicholas
Publication type:
Article
PIK3CA mutation enrichment and quantitation from blood and tissue.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-74086-w
By:
- Keraite, Ieva;
- Alvarez-Garcia, Virginia;
- Garcia-Murillas, Isaac;
- Beaney, Matthew;
- Turner, Nicholas C.;
- Bartos, Clare;
- Oikonomidou, Olga;
- Kersaudy-Kerhoas, Maïwenn;
- Leslie, Nicholas R.
Publication type:
Article
Reproducibility of Digital PCR Assays for Circulating Tumor DNA Analysis in Advanced Breast Cancer.
Published in:
PLoS ONE, 2016, v. 11, n. 10, p. 1, doi. 10.1371/journal.pone.0165023
By:
- Hrebien, Sarah;
- O’Leary, Ben;
- Beaney, Matthew;
- Schiavon, Gaia;
- Fribbens, Charlotte;
- Bhambra, Amarjit;
- Johnson, Richard;
- Garcia-Murillas, Isaac;
- Turner, Nicholas
Publication type:
Article
Early circulating tumor DNA dynamics and clonal selection with palbociclib and fulvestrant for breast cancer.
Published in:
Nature Communications, 2018, v. 9, p. 1, doi. 10.1038/s41467-018-03215-x
By:
- O’Leary, Ben;
- Hrebien, Sarah;
- Morden, James P.;
- Beaney, Matthew;
- Fribbens, Charlotte;
- Xin Huang;
- Yuan Liu;
- Bartlett, Cynthia Huang;
- Koehler, Maria;
- Cristofanilli, Massimo;
- Garcia-Murillas, Isaac;
- Bliss, Judith M.;
- Turner, Nicholas C.
Publication type:
Article
Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance.
Published in:
Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-01864-y
By:
- Martin, Lesley-Ann;
- Ribas, Ricardo;
- Simigdala, Nikiana;
- Schuster, Eugene;
- Pancholi, Sunil;
- Tenev, Tencho;
- Gellert, Pascal;
- Buluwela, Laki;
- Harrod, Alison;
- Thornhill, Allan;
- Nikitorowicz-Buniak, Joanna;
- Bhamra, Amandeep;
- Turgeon, Marc-Olivier;
- Poulogiannis, George;
- Gao, Qiong;
- Martins, Vera;
- Hills, Margaret;
- Garcia-Murillas, Isaac;
- Fribbens, Charlotte;
- Patani, Neill
Publication type:
Article
Circulating Tumor DNA Markers for Early Progression on Fulvestrant With or Without Palbociclib in ER+ Advanced Breast Cancer.
Published in:
2021
By:
- O'Leary, Ben;
- Cutts, Rosalind J;
- Huang, Xin;
- Hrebien, Sarah;
- Liu, Yuan;
- André, Fabrice;
- Loibl, Sibylle;
- Loi, Sherene;
- Garcia-Murillas, Isaac;
- Cristofanilli, Massimo;
- Bartlett, Cynthia Huang;
- Turner, Nicholas C
Publication type:
journal article
Next Generation Sequencing Assay for Detection of Circulating HPV DNA (cHPV-DNA) in Patients Undergoing Radical (Chemo)Radiotherapy in Anal Squamous Cell Carcinoma (ASCC).
Published in:
Frontiers in Oncology, 2020, v. 10, p. 1, doi. 10.3389/fonc.2020.00505
By:
- Lee, Jen Y.;
- Cutts, Rosalind J.;
- White, Ingrid;
- Augustin, Yolanda;
- Garcia-Murillas, Isaac;
- Fenwick, Kerry;
- Matthews, Nik;
- Turner, Nicholas C.;
- Harrington, Kevin;
- Gilbert, Duncan C.;
- Bhide, Shreerang
Publication type:
Article

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