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- Title
Mechanism of action of immunomodulatory agents in multiple myeloma.
- Authors
Reske, Thomas; Fulciniti, Mariateresa; Munshi, Nikhil C.
- Abstract
Immunomodulatory agents (IMiD’s) have become an important drug category in the treatment of multiple myeloma. The agents have a complex mechanism of action that influence the microenvironment in the bone marrow. The microenvironment is an essential promotor of disease progression and therefore important in targeting the disease. The article reviews mechanism of action and essential pathways of IMiD’s that are important in disease treatment.
- Subjects
IMMUNOLOGICAL adjuvants; MULTIPLE myeloma treatment; BIOCHEMICAL mechanism of action; BONE marrow; DISEASE progression
- Publication
Medical Oncology, 2010, Vol 27, p7
- ISSN
1357-0560
- Publication type
Article
- DOI
10.1007/s12032-010-9527-y