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A Biochemical and Biophysical Analysis of the Interaction of nsp9 with nsp12 from SARS‐CoV‐2—Implications for Future Drug Discovery Efforts.
- Published in:
- Proteins, 2024, v. 92, n. 11, p. 1308, doi. 10.1002/prot.26725
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- Publication type:
- Article
The carboxy-terminal coiled-coil of the RNA polymerase β′-subunit is the main binding site for Gre factors.
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- EMBO Reports, 2007, v. 8, n. 11, p. 1038, doi. 10.1038/sj.embor.7401079
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- Article
Initial Events in Bacterial Transcription Initiation.
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- Biomolecules (2218-273X), 2015, v. 5, n. 2, p. 1035, doi. 10.3390/biom5021035
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- Article
Allosteric couplings upon binding of RfaH to transcription elongation complexes.
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- Nucleic Acids Research, 2022, v. 50, n. 11, p. 6384, doi. 10.1093/nar/gkac453
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- Publication type:
- Article
Positive supercoiling favors transcription elongation through lac repressor-mediated DNA loops.
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- Nucleic Acids Research, 2022, v. 50, n. 5, p. 2826, doi. 10.1093/nar/gkac093
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- Publication type:
- Article
NMPylation and de-NMPylation of SARS-CoV-2 nsp9 by the NiRAN domain.
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- Nucleic Acids Research, 2021, v. 49, n. 15, p. 8822, doi. 10.1093/nar/gkab677
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- Publication type:
- Article
Flipping states: a few key residues decide the winning conformation of the only universally conserved transcription factor.
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- Nucleic Acids Research, 2017, v. 45, n. 15, p. 8835, doi. 10.1093/nar/gkx523
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- Publication type:
- Article
Distributed biotin-streptavidin transcription roadblocks for mapping cotranscriptional RNA folding.
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- Nucleic Acids Research, 2017, v. 45, n. 12, p. 1, doi. 10.1093/nar/gkx233
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- Publication type:
- Article
Interplay between the trigger loop and the F loop during RNA polymerase catalysis.
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- Nucleic Acids Research, 2014, v. 42, n. 1, p. 544, doi. 10.1093/nar/gkt877
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- Publication type:
- Article
Interdomain contacts control folding of transcription factor RfaH.
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- Nucleic Acids Research, 2013, v. 41, n. 22, p. 10077, doi. 10.1093/nar/gkt779
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- Publication type:
- Article
Ubiquitous transcription factors display structural plasticity and diverse functions.
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- BioEssays, 2015, v. 37, n. 3, p. 324, doi. 10.1002/bies.201400177
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- Publication type:
- Article
Functional specialization of transcription elongation factors.
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- EMBO Journal, 2009, v. 28, n. 2, p. 112, doi. 10.1038/emboj.2008.268
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- Publication type:
- Article
All it takes to express virulence genes (361.3).
- Published in:
- FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.361.3
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- Publication type:
- Article
Going Retro, Going Viral: Experiences and Lessons in Drug Discovery from COVID-19.
- Published in:
- Molecules, 2022, v. 27, n. 12, p. 3815, doi. 10.3390/molecules27123815
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- Publication type:
- Article
NusG, an Ancient Yet Rapidly Evolving Transcription Factor.
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- Frontiers in Microbiology, 2021, v. 11, p. N.PAG, doi. 10.3389/fmicb.2020.619618
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- Article
Role of a Zn-independent DksA in Zn homeostasis and stringent response.
- Published in:
- Molecular Microbiology, 2011, v. 79, n. 3, p. 700, doi. 10.1111/j.1365-2958.2010.07475.x
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- Publication type:
- Article
A processive riboantiterminator seeks a switch to make biofilms.
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- Molecular Microbiology, 2010, v. 76, n. 3, p. 535, doi. 10.1111/j.1365-2958.2010.07133.x
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- Publication type:
- Article
Functional regions of the N-terminal domain of the antiterminator RfaH.
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- Molecular Microbiology, 2010, v. 76, n. 2, p. 286, doi. 10.1111/j.1365-2958.2010.07056.x
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- Publication type:
- Article
Post-initiation control by the initiation factor sigma.
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- Molecular Microbiology, 2008, v. 68, n. 1, p. 1, doi. 10.1111/j.1365-2958.2008.06136.x
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- Publication type:
- Article
CBR antimicrobials alter coupling between the bridge helix and the β subunit in RNA polymerase.
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- Nature Communications, 2014, v. 5, n. 3, p. 3408, doi. 10.1038/ncomms4408
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- Publication type:
- Article
Machine Learning Suggests That Small Size Helps Broaden Plasmid Host Range.
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- Genes, 2023, v. 14, n. 11, p. 2044, doi. 10.3390/genes14112044
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- Article
Molecular biology: The tug of DNA repair.
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- Nature, 2014, v. 505, n. 7483, p. 298, doi. 10.1038/nature12850
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- Article
The δ subunit and NTPase HelD institute a two-pronged mechanism for RNA polymerase recycling.
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- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-20159-3
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- Publication type:
- Article
DksA2, a zinc-independent structural analog of the transcription factor DksA
- Published in:
- FEBS Letters, 2013, v. 587, n. 6, p. 614, doi. 10.1016/j.febslet.2013.01.073
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- Publication type:
- Article
A structural analysis of the nsp9 protein from the coronavirus MERS CoV reveals a conserved RNA binding interface.
- Published in:
- Proteins, 2024, v. 92, n. 3, p. 418, doi. 10.1002/prot.26630
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- Publication type:
- Article
Termination and antitermination: RNA polymerase runs a stop sign.
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- Nature Reviews Microbiology, 2011, v. 9, n. 5, p. 319, doi. 10.1038/nrmicro2560
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- Publication type:
- Article
A non‐native C‐terminal extension of the β' subunit compromises RNA polymerase and Rho functions.
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- Molecular Microbiology, 2022, v. 117, n. 4, p. 871, doi. 10.1111/mmi.14879
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- Publication type:
- Article
The dormancy‐specific regulator, SutA, is intrinsically disordered and modulates transcription initiation in Pseudomonas aeruginosa.
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- Molecular Microbiology, 2019, v. 112, n. 3, p. 992, doi. 10.1111/mmi.14337
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- Publication type:
- Article
In silico discovery of small molecules that inhibit RfaH recruitment to RNA polymerase.
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- Molecular Microbiology, 2018, v. 110, n. 1, p. 128, doi. 10.1111/mmi.14093
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- Article
Locking the nontemplate DNA to control transcription.
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- Molecular Microbiology, 2018, v. 109, n. 4, p. 445, doi. 10.1111/mmi.13983
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- Article
Rebuilding the bridge between transcription and translation.
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- Molecular Microbiology, 2018, v. 108, n. 5, p. 467, doi. 10.1111/mmi.13964
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- Publication type:
- Article
pH Dependence of the Stress Regulator DksA.
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- PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0120746
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- Article
Fidaxomicin Is an Inhibitor of the Initiation of Bacterial RNA Synthesis.
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- Clinical Infectious Diseases, 2012, v. 55, n. suppl_2, p. S127, doi. 10.1093/cid/cis358
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- Article
Structural basis for transcription inhibition by tagetitoxin.
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- Nature Structural & Molecular Biology, 2005, v. 12, n. 12, p. 1086, doi. 10.1038/nsmb1015
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- Article
Transcription inactivation through local refolding of the RNA polymerase structure.
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- 2009
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- Publication type:
- Letter
Structural basis for substrate loading in bacterial RNA polymerase.
- Published in:
- Nature, 2007, v. 448, n. 7150, p. 163, doi. 10.1038/nature05931
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- Publication type:
- Article
Structural basis for transcription elongation by bacterial RNA polymerase.
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- Nature, 2007, v. 448, n. 7150, p. 157, doi. 10.1038/nature05932
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- Publication type:
- Article
A novel non-radioactive primase–pyrophosphatase activity assay and its application to the discovery of inhibitors of Mycobacterium tuberculosis primase DnaG.
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- Nucleic Acids Research, 2013, v. 41, n. 4, p. e56, doi. 10.1093/nar/gks1292
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- Article
Transcription initiation factor DksA has diverse effects on RNA chain elongation.
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- Nucleic Acids Research, 2012, v. 40, n. 8, p. 3392, doi. 10.1093/nar/gkr1273
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- Publication type:
- Article
Functional analysis of Thermus thermophilus transcription factor NusG.
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- Nucleic Acids Research, 2010, v. 38, n. 21, p. 7432, doi. 10.1093/nar/gkq623
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- Publication type:
- Article
Multiple roles of the RNA polymerase β′ SW2 region in transcription initiation, promoter escape, and RNA elongation.
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- Nucleic Acids Research, 2010, v. 38, n. 17, p. 5784, doi. 10.1093/nar/gkq355
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- Publication type:
- Article
Allosteric control of the RNA polymerase by the elongation factor RfaH.
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- Nucleic Acids Research, 2007, v. 35, n. 17, p. 5694, doi. 10.1093/nar/gkm600
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- Publication type:
- Article
Force and the α-C-terminal domains bias RNA polymerase recycling.
- Published in:
- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-51603-3
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- Publication type:
- Article
Sm-like protein Rof inhibits transcription termination factor ρ by binding site obstruction and conformational insulation.
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- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-47439-6
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- Publication type:
- Article
Reciprocating RNA Polymerase batters through roadblocks.
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- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-47531-x
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- Article
Mechanism of chromatin remodeling and recovery during passage of RNA polymerase II.
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- Nature Structural & Molecular Biology, 2009, v. 16, n. 12, p. 1272, doi. 10.1038/nsmb.1689
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- Publication type:
- Article
Merging the RNA and DNA worlds.
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- Nature Structural & Molecular Biology, 2007, v. 14, n. 12, p. 1122, doi. 10.1038/nsmb1207-1122
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- Publication type:
- Article
Transcription activation by the bacteriophage Mu Mor protein: analysis of promoter mutations in P<sub>m</sub> identifies a new region required for promoter function.
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- Nucleic Acids Research, 1996, v. 24, n. 3, p. 450, doi. 10.1093/nar/24.3.450
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- Publication type:
- Article
Reversible fold-switching controls the functional cycle of the antitermination factor RfaH.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-08567-6
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- Publication type:
- Article
Interdomain Contacts Control Native State Switching of RfaH on a Dual-Funneled Landscape.
- Published in:
- PLoS Computational Biology, 2015, v. 11, n. 7, p. 1, doi. 10.1371/journal.pcbi.1004379
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- Publication type:
- Article