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- Title
Value of 18-F-FDG PET/CT and CT in the Diagnosis of Indeterminate Adrenal Masses.
- Authors
Launay, Nathalie; Silvera, Stéphane; Tenenbaum, Florence; Groussin, Lionel; Tissier, Frédérique; Audureau, Etienne; Vignaux, Olivier; Dousset, Bertrand; Bertagna, Xavier; Legmann, Paul
- Abstract
The purpose of this paper was to study the value of 18-FDG PET/CT and reassess the value of CT for the characterization of indeterminate adrenal masses. 66 patients with 67 indeterminate adrenal masses were included in our study. CT/MRI images and 18F-FDG PET/CT data were evaluated blindly for tumor morphology, enhancement features, apparent diffusion coefficient values, maximum standardized uptake values, and adrenal-to-liver maxSUV ratio. The study population comprised pathologically confirmed 16 adenomas, 19 metastases, and 32 adrenocortical carcinomas. Macroscopic fat was observed in 62.5% of the atypical adenomas at CT but not in malignant masses. On 18F-FDG PET/CT, SUVmax and adrenal-to-liver maxSUV ratio were significantly lower in adenomas than in malignant tumors. An SUVmax value of less than 3.7 or an adrenal-to-liver maxSUV ratio of less than 1.29 is highly predictive of benignity.
- Subjects
FLUORODEOXYGLUCOSE F18; POSITRON emission tomography; COMPUTED tomography; ADRENAL tumors; MAGNETIC resonance imaging of cancer; PATIENTS; DIAGNOSIS
- Publication
International Journal of Endocrinology, 2015, Vol 2015, p1
- ISSN
1687-8337
- Publication type
Article
- DOI
10.1155/2015/213875