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- Title
Inhibition of astrocytic glycine transporter-1: friend or foe for ameliorating NMDA receptor hypofunction?
- Authors
Singer, Philipp; Yee, Benjamin K.
- Abstract
This document is a compilation of scientific articles and studies that explore the role of glycine transporters in schizophrenia and other psychiatric disorders. The articles discuss the mechanisms of glycine release and the potential therapeutic targets for treating schizophrenia. They also examine the effects of glycine augmentation on symptoms and explore the use of glycine transporter inhibitors as potential treatments for cognitive impairment and negative symptoms associated with schizophrenia. The document provides a comprehensive overview of current research in this field and may be useful for library patrons conducting research on schizophrenia and its treatment options.
- Subjects
GLYCINE receptors; METHYL aspartate receptors; GLUTAMATE receptors; GLYCINE; CLINICAL trials
- Publication
Frontiers in Cellular Neuroscience, 2024, p1
- ISSN
1662-5102
- Publication type
Article
- DOI
10.3389/fncel.2024.1389718