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- Title
Significant Liver-Related Morbidity After Bariatric Surgery and Its Reversal—a Case Series.
- Authors
Eilenberg, Magdalena; Langer, Felix B.; Prager, Gerhard; Beer, Andrea; Trauner, Michael; Staufer, Katharina
- Abstract
Background: Nonalcoholic fatty liver disease (NAFLD) occurs in up to 80% of patients with obesity. Current data suggest an improvement of NAFLD after established bariatric procedures.Objectives: This study investigated liver function impairment after Roux-en-Y gastric bypass (RYGB) and one-anastomosis gastric bypass (OAGB).Setting: University Hospital, Bariatric Surgery UnitMethods: In this single-center case series, consecutive in- and outpatients after bariatric surgery who presented with severe liver dysfunction from March 2014 to February 2017 were included and followed until March 2017.Results: In total, 10 patients (m:f = 2:8; median age 48 years, range 22–66 years) were included. Liver dysfunction occurred after a median postoperative time of 15 months (range 2–88 months). Median %excess weight loss at that time was 110.6% (range 85.2–155.5%). Liver steatosis/fibrosis occurred in 70%, cirrhosis in 30% of patients, and led to fatigue (90%), ascites (70%), hepatic encephalopathy (30%), and upper gastrointestinal bleeding (20%). Elevation of transaminases, impairment of coagulation parameters, thrombocytopenia, and hypoalbuminemia were present in 70, 80, 70, and 100%, respectively. In eight patients, lengthening of the alimentary/common limb led to an improvement or complete remission of symptoms. In one patient, liver transplantation was required, one patient deceased due to septic shock and decompensated liver disease.Conclusions: Severe liver dysfunction may also occur after bariatric procedures such as OAGB and RYGB. A comprehensive, meticulous follow-up for early identification of postoperative liver impairment should be aspired. Bypass length reduction led to a fast improvement in all patients.
- Subjects
BARIATRIC surgery; FATTY liver; GASTRIC bypass; WEIGHT loss; METABOLIC syndrome
- Publication
Obesity Surgery, 2018, Vol 28, Issue 3, p812
- ISSN
0960-8923
- Publication type
Article
- DOI
10.1007/s11695-017-2925-x