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- Title
Impact of unilateral dual-brachial arteries on endothelial-dependent and endothelial-independent vasodilation: a case study.
- Authors
Courish, Molly K.; Shivgulam, Madeline E.; MacLeod, Jessica R.; Kimmerly, Derek S.; O'Brien, Myles W.
- Abstract
Brachial artery bifurcation has been documented in ∼5%–10% of cadaver models, but our understanding of arterial function in these rare cases is unknown. This case study examined vasodilatory responses between a right bifurcated (right superficial brachial artery, right deep brachial artery) versus a left nonbifurcated brachial artery in a 28-year-old healthy female. Vasodilatory functions were assessed via flow-mediated dilation and nitroglycerin-mediated dilation (0.4 mg sublingual spray) techniques. Bifurcation of the brachial artery promotes lower endothelial-dependent vasodilation and possibly reduced vascular smooth muscle responsiveness to nitric oxide. Our case study indicated that a bifurcated brachial artery exhibited worse vasodilatory responses relative to an intact contralateral artery.
- Subjects
ENDOTHELIUM physiology; SMOOTH muscle physiology; BRACHIAL artery; NITROGLYCERIN; VASODILATION; HEMODYNAMICS; NITRIC oxide; BLOOD flow measurement
- Publication
Applied Physiology, Nutrition & Metabolism, 2023, Vol 48, Issue 12, p1019
- ISSN
1715-5312
- Publication type
Article
- DOI
10.1139/apnm-2023-0170