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- Title
Extracellular vesicle-mediated transfer of membranous components from the highly malignant T24 urinary carcinoma cell line to the non-malignant RT4 urinary papilloma cell line.
- Authors
Ogorevc, Eva; Hudoklin, Samo; Veranič, Peter; Kralj-Iglič, Veronika
- Abstract
This communication reports the first experimental evidence that in the bladder cancer model, membranous components labelled with the DiO dye and the cholera toxin subunit B can be transported from highly malignant (T24) to non-malignant (RT4) cells by extracellular vesicles. Taking into account the presence of stable membranous nanostructures found by scanning electron microscopy, we suggest a possible uptake mechanism in recipient cells through fusion with highly curved membranous regions.
- Subjects
BLADDER cancer; CANCER cells; SCANNING electron microscopy; CHOLERA toxin; NANOSTRUCTURED materials
- Publication
Protoplasma, 2014, Vol 251, Issue 3, p699
- ISSN
0033-183X
- Publication type
Article
- DOI
10.1007/s00709-013-0544-5