We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Olanzapine-induced electroencephalographic changes reversed by lamotrigine.
- Authors
Velur, Prasuna L.; Kalamangalam, Giridhar P.
- Abstract
The atypical neuroleptic, olanzapine (OLZ), may induce electroencephalographic (EEG) abnormalities. The anticonvulsant, lamotrigine (LMG), reduces interictal epileptiform discharges and is effective in seizures in patients with both primary and partial epilepsy syndromes. The effect of LMG on neuroleptic-induced EEG abnormalities has not been previously reported. We describe the case of a 13-year-old male with paroxysmal nonepileptic spells who underwent diagnostic video-EEG telemetry, whose abnormal OLZ-induced EEG findings were strikingly affected by LTG withdrawal and reintroduction. The effect of LTG in normalizing EEG changes in suspected epilepsy caused by atypical neuroleptics is discussed.
- Subjects
SEIZURES (Medicine); DRUG side effects; ELECTROENCEPHALOGRAPHY; SPASMS; LAMOTRIGINE; OLANZAPINE
- Publication
Annals of Indian Academy of Neurology, 2012, Vol 15, Issue 4, p313
- ISSN
0972-2327
- Publication type
Article
- DOI
10.4103/0972-2327.104345