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- Title
Pathology type does not predict language lateralization in children with medically intractable epilepsy.
- Authors
Kadis, Darren S.; Kerr, Elizabeth N.; Rutka, James T.; Snead III, O. Carter; Weiss, Shelly K.; Smith, Mary Lou
- Abstract
We examined potential differences in the effects of pathology type on language lateralization in pediatric epilepsy. We examined findings from intracarotid sodium amobarbital procedure (IAP/Wada) in a large consecutive sample of children with refractory epilepsy. Subjects were assigned to one of three pathology groups: developmental (n = 28), acquired (n = 26), and tumor (n = 20); groups were compared for language lateralization. Rates of atypical language lateralization did not differ across groups. Greater than half of the subjects with left hemisphere insults and seizure onset before 6 years of age had atypical language lateralization, independent of pathology type. Atypical language lateralization may occur in the context of developmental, acquired, and/or tumor pathology.
- Subjects
CHILDHOOD epilepsy; DIAGNOSIS of epilepsy; WADA test; CEREBRAL dominance testing; DIAGNOSTIC use of amobarbital; NEUROLOGIC examination
- Publication
Epilepsia (Series 4), 2009, Vol 50, Issue 6, p1498
- ISSN
0013-9580
- Publication type
Article
- DOI
10.1111/j.1528-1167.2008.02014.x