We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
The enzymology of human eicosanoid pathways: the lipoxygenase branches.
- Authors
Biringer, Roger Gregory
- Abstract
Eicosanoids are short-lived derivatives of polyunsaturated fatty acids that serve as autocrine and paracrine signaling molecules. They are involved numerous biological processes of both the well state and disease states. A thorough understanding of the progression the disease state and homeostasis of the well state requires a complete evaluation of the systems involved. This review examines the enzymology for the enzymes involved in the production of eicosanoids along the lipoxygenase branches of the eicosanoid pathways with particular emphasis on those derived from arachidonic acid. The enzymatic parameters, protocols to measure them, and proposed catalytic mechanisms are presented in detail.
- Subjects
UNSATURATED fatty acids; ARACHIDONIC acid; ENZYMOLOGY; FATTY acid derivatives; DISEASE progression; EICOSANOIDS
- Publication
Molecular Biology Reports, 2020, Vol 47, Issue 9, p7189
- ISSN
0301-4851
- Publication type
Article
- DOI
10.1007/s11033-020-05698-8