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- Title
Image quality at synthetic brain magnetic resonance imaging in children.
- Authors
Lee, So; Choi, Young; Cheon, Jung-Eun; Kim, In-One; Cho, Seung; Kim, Won; Kim, Hye; Cho, Hyun-Hae; You, Sun-Kyoung; Park, Sook-Hyun; Hwang, Moon; Lee, So Mi; Choi, Young Hun; Cho, Seung Hyun; Kim, Won Hwa; Kim, Hye Jung; Hwang, Moon Jung
- Abstract
<bold>Background: </bold>The clinical application of the multi-echo, multi-delay technique of synthetic magnetic resonance imaging (MRI) generates multiple sequences in a single acquisition but has mainly been used in adults.<bold>Objective: </bold>To evaluate the image quality of synthetic brain MR in children compared with that of conventional images.<bold>Materials and Methods: </bold>Twenty-nine children (median age: 6 years, range: 0-16 years) underwent synthetic and conventional imaging. Synthetic (T2-weighted, T1-weighted and fluid-attenuated inversion recovery [FLAIR]) images with settings matching those of the conventional images were generated. The overall image quality, gray/white matter differentiation, lesion conspicuity and image degradations were rated on a 5-point scale. The relative contrasts were assessed quantitatively and acquisition times for the two imaging techniques were compared.<bold>Results: </bold>Synthetic images were inferior due to more pronounced image degradations; however, there were no significant differences for T1- and T2-weighted images in children <2 years old. The quality of T1- and T2-weighted images were within the diagnostically acceptable range. FLAIR images showed greatly reduced quality. Gray/white matter differentiation was comparable or better in synthetic T1- and T2-weighted images, but poorer in FLAIR images. There was no effect on lesion conspicuity. Synthetic images had equal or greater relative contrast. Acquisition time was approximately two-thirds of that for conventional sequences.<bold>Conclusion: </bold>Synthetic T1- and T2-weighted images were diagnostically acceptable, but synthetic FLAIR images were not. Lesion conspicuity and gray/white matter differentiation were comparable to conventional MRI.
- Subjects
PEDIATRICS; DIAGNOSTIC imaging; IMAGE quality analysis; MAGNETIC resonance imaging; NEWBORN infant care
- Publication
Pediatric Radiology, 2017, Vol 47, Issue 12, p1638
- ISSN
0301-0449
- Publication type
journal article
- DOI
10.1007/s00247-017-3913-y