The article discusses the developments on drugs that fight multiple myeloma, such as proteasome inhibitors and immunomodulators. It says that the proteasome inhibitor bortezomib, has hinted effectiveness against myeloma cells but posed various side effects such as severe nausea and pains in hands and feet. It mentions that the immunomodulators such as the lenalidomide, was preferred over thalidomide due to the side effect peripheral neuropathy.