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- Title
Drug-Eluting Stents for Treatment of Peripheral Artery Disease.
- Authors
Abdullah, Kazeen; Bou Dargham, Bassel; Sun, Bo; Steinbrecher, Micah; Khalili, Houman; Banerjee, Subhash; Brilakis, Emmanouil S.; Huiqiang, Zhao
- Abstract
Endovascular intervention is a mainstay treatment of peripheral artery disease (PAD) in addition to aggressive risk factor modification and exercise programs in patients with favorable anatomy or in those who are considered too high risk for surgical intervention. Treatment with percutaneous transluminal angioplasty (PTA) and bare metal stents (BMS) has been limited by high rates of in-stent restenosis (ISR) requiring repeat revascularization. Drug-eluting stents (DES), developed and designed to reduce ISR, offer a promising solution to the current challenges in endovascular management of PAD. Several randomized clinical trials have shown improved short- and mid-term outcomes with DES as compared with both PTA and BMS. Herein we provide an up-to-date review of the current literature on DES use in PAD.
- Subjects
CORONARY restenosis prevention; CARDIOVASCULAR surgery; COMPLICATIONS of prosthesis; PERIPHERAL vascular diseases; SURGICAL complications; TRANSLUMINAL angioplasty; SYSTEMATIC reviews; TREATMENT effectiveness; REVASCULARIZATION (Surgery); DRUG-eluting stents; DISEASE risk factors
- Publication
American Journal of Cardiovascular Drugs, 2018, Vol 18, Issue 3, p175
- ISSN
1175-3277
- Publication type
Article
- DOI
10.1007/s40256-018-0265-4