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- Title
Pythium insidiosum: A Rare Necrotizing Orbital and Facial Infection.
- Authors
Kirzhner, Maria; Arnold, Sandra R.; Lyle, Cari; Mendoza, Leonel L.; Fleming, James C.
- Abstract
Pythium insidiosum, also known as “swamp cancer,” has been long known for its destructive effects on plants and animals. Infections with this fungus-like organism typically occur in temperate, tropical, and subtropical regions [1]. Human infection with P insidiosum, although exceedingly rare, is characterized by invasion of the cornea, cutaneous, subcutaneous, and orbital tissues with eosinophilic, tumor-like masses demonstrating arterial tropism [1, 2]. In most cases, patients have a history of recent exposure to wet environments [1]. If left untreated, P insidiosum is fatal, because it is an angioinvasive organism that leads to thrombosis and tissue ischemia. Reports of most human cases are from Thailand, with only 4 well documented orbital cases to date in the United States and Australia [1, 3, 4].
- Subjects
PYTHIUM diseases; PYTHIUM; THROMBOSIS; ISCHEMIA
- Publication
Journal of the Pediatric Infectious Diseases Society, 2015, Vol 4, Issue 1, pe10
- ISSN
2048-7193
- Publication type
Case Study
- DOI
10.1093/jpids/piu015